DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbce and PFI

DIOPT Version :9

Sequence 1:	NP_610197.2	Gene:	Tbce / 35532	FlyBaseID:	FBgn0033055	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_565017.1	Gene:	PFI / 843485	AraportID:	AT1G71440	Length:	531	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	154/541 - (28%)
Similarity:	255/541 - (47%)	Gaps:	57/541 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGTRI-KIGDN--YGTVRYVGEVSGHMGSWLGIEWDDGLRGKHNGIVDGKRYFQTQTPTGGSFIR 75
            :|.|: .:.|:  .|||:|||:|.|:.|:|:|::||....|||||.|:|..||..::.:..||:|
plant    12 IGQRVHSLNDSRRVGTVKYVGDVEGYSGTWIGVDWDQDGDGKHNGSVNGVFYFNGRSQSSASFVR 76

  Fly    76 PGKVGPCATLEDAARERYLNYDSSNVDESLIREAQASLQASLFEVVGMDKIARKQSKFEQLEEVS 140
            ...:....||..|...||....:.:.::.:...:..:.:.|: :::|.|||..|.|:||:|...|
plant    77 SQNLSRGITLLQALELRYRTISTKDEEDEMYVLSAGNRRVSI-QLLGGDKIQDKLSRFEELTSAS 140

  Fly   141 VDQTPVNAAGYLKE----LTHLTTLNVSHTLIWNWEIVASIAQQLPSLTNLNLSSNRLVLPTSSQ 201
            :....|::.|...:    |.:|..|:::..||.:||.:.::.:|||:||.||||.|.|    ||.
plant   141 LSYLGVSSLGVSSDLGSILPNLKLLDLTGNLISDWEEIGALCEQLPALTTLNLSCNSL----SSD 201

  Fly   202 ITELEPSFRQLKRINLRSCGFSDWKDVMHTALLWPNILSLGLQENSLGQLAEVDRT--KIFKQLH 264
            |..| |..:.::.:.|.:.|.| |..|.......|.|..|.|..|.:..:.....:  :.|..|.
plant   202 IKSL-PQLKNIRVLVLNNSGLS-WTQVEILRRSLPGIEELHLMGNMISTITSTSSSDDQAFNSLR 264

  Fly   265 ELDLHRTNIMDFDQVTKLGNLTTLRLLNIMENGIEEI--KLPDCDSQEK-LNIFVSLEQLNLLHN 326
            .|:|....|.|:.:|.||..|..|..|.:.:|.:..|  .:...:|.|| .:.|.||..|.|..|
plant   265 LLNLDDNCISDWSEVLKLSQLPCLEQLYLNKNKLSRIFQSVNGTESSEKGSDPFPSLSCLLLGAN 329

  Fly   327 PIWNEA--DAFNELDKLPQLKRLSKTP---HLKSNFDEMFSKAVASIASLQFINKAEVTAEQRRG 386
            .|.:.|  ||.|...:|..: |||:.|   .::.......  .||.:..:|.:|.:||.|.:::.
plant   330 NIGDLASVDALNGFPQLVDI-RLSENPISDPVRGGVPRFV--LVARLTKVQVLNGSEVRAREKKD 391

  Fly   387 AEYDIWKKYALDWMQATQGGTDSLREFCRRHRTYPLLVKKYG------SPADFVPRSQAKQSNLI 445
            :|.. :.:..:..:....|..:.|      |..:..|.|.:|      |..:..|::.|  |.||
plant   392 SEIR-YVRMVMSKLNDKSGEIELL------HPRFYELKKLHGIEDERASAENSGPKNIA--SGLI 447

  Fly   446 NVSI---------RHQLTGETWEKKVPRMITVQTLQGLVMKRFRLSGDVPQLCYVDALHPDLVVP 501
            ::::         :..||     ||:|..|||..|:.|....|:|....|:|...:...| ....
plant   448 SITLKCVGPSMGEKPHLT-----KKLPGSITVGKLKILSENFFKLKSIKPRLFLQEEGSP-FPTA 506

  Fly   502 LDNNAKTLDFYSVQEHDTVLV 522
            ||:...||....:.:..|:||
plant   507 LDDETATLLDVGICDGSTLLV 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbce	NP_610197.2	CAP_GLY	14..79	CDD:214997	28/67 (42%)
		LRR_RI	<148..268	CDD:330982	37/125 (30%)
		leucine-rich repeat	158..183	CDD:275380	8/24 (33%)
		leucine-rich repeat	184..211	CDD:275380	13/26 (50%)
		leucine-rich repeat	212..238	CDD:275380	6/25 (24%)
		leucine-rich repeat	239..262	CDD:275380	4/24 (17%)
		leucine-rich repeat	263..287	CDD:275380	9/23 (39%)
		leucine-rich repeat	288..317	CDD:275380	8/31 (26%)
		leucine-rich repeat	318..343	CDD:275380	10/26 (38%)
PFI	NP_565017.1	CAP_GLY	12..81	CDD:214997	28/68 (41%)
		leucine-rich repeat	136..161	CDD:275380	5/24 (21%)
		PPP1R42	157..384	CDD:411060	70/235 (30%)
		leucine-rich repeat	162..187	CDD:275380	8/24 (33%)
		leucine-rich repeat	188..210	CDD:275380	13/26 (50%)
		leucine-rich repeat	211..225	CDD:275380	4/14 (29%)
		leucine-rich repeat	236..262	CDD:275380	5/25 (20%)
		leucine-rich repeat	263..287	CDD:275380	9/23 (39%)
		leucine-rich repeat	288..320	CDD:275380	8/31 (26%)
		leucine-rich repeat	321..345	CDD:275380	9/23 (39%)
		Ubl_TBCE	446..528	CDD:340564	24/88 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3696
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37744
Inparanoid	1	1.050	154	1.000	Inparanoid score	I1687
OMA	1	1.010	-	-		QHG54570
OrthoDB	1	1.010	-	-		D249920at2759
OrthoFinder	1	1.000	-	-		FOG0004303
OrthoInspector	1	1.000	-	-		oto3021
orthoMCL	1	0.900	-	-		OOG6_102729
Panther	1	1.100	-	-	LDO	PTHR15140
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4087
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.940