Protein Alignment Tbce and Tbce

DIOPT Version :10

• Sequence 1: NP_610197.2
• Gene: Tbce / 35532
• FlyBaseID: FBgn0033055
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_848027.1
• Gene: Tbce / 70430
• MGIID: 1917680
• Length: 524
• Species: Mus musculus
• Alignment Length: 525
• Identity: 169/525 - (32%)
• Similarity: 274/525 - (52%)
• Gaps: 26/525 - (4%)

  Fly    14 LGTRIKIGDNYGTVRYVGEVSGHMGSWLGIEWDDGLRGKHNGIVDGKRYFQTQTPTGGSFIRPGK 78
            :|.|:::...|.|||:.|.|....|.|||:|||:..||||:|..:|..||:.:.||||||:||.|
Mouse    10 IGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPTGGSFVRPSK 74

  Fly    79 VGPCATLEDAARERYLNYDSSNVDESLIREAQASLQASLFEVVGMDKIARKQSKFEQLEEVSVDQ 143
            |........|.::||:..|..:.||:.......|.|.   :.:|.:.|.:|||:...|:::|:..
Mouse    75 VNFGDDFLTALKKRYVLEDGPDDDENSCSLKVGSKQV---QTIGFEHITKKQSQLRALQDISLWN 136

  Fly   144 TPVNAAG----YLKELTHLTTLNVSHTLIWNWEIVASIAQQLPSLTNLNLSSNRLVLPTSSQITE 204
            ..|:.||    ..:...::..:|:|..|:..|:.|..||:||..|..|:||.|:|..|:.|  ..
Mouse   137 CAVSHAGEQGRIAEACPNIRVVNLSKNLLSTWDEVVLIAEQLKDLEALDLSENKLQFPSDS--PT 199

  Fly   205 LEPSFRQLKRINLRSCGFSDWKDVMHTALLWPNILSLGLQENSLGQLAEVDRTKIFKQLHELDLH 269
            |..:|..||.:.|...|.: |.:|:|.|..||.:..|.|:.|:: .::| ....:.:::..|||.
Mouse   200 LTRTFSTLKTLVLNKTGIT-WTEVLHCAPSWPVLEELYLKSNNI-SISE-RPVNVLQKMRLLDLS 261

  Fly   270 RTNIMDFDQVTKLGNLTTLRLLNIMENGIEEIKLPDCDSQEKLNIFVSLEQLNLLHNPIWNEADA 334
            ....:|..|::.:.:|..|..|.:.:.|:..|..||.:...|.::|.:|:.|.:..|.| :|...
Mouse   262 SNPSIDESQLSLIADLPRLEHLVLSDIGLSSIHFPDAEIGCKTSMFPALKYLIVNDNQI-SEWSF 325

  Fly   335 FNELDKLPQLKRLSKTPHLKSNFDEMFSKAVASIASLQFINKAEVTAEQRRGAEYDIWKKYALDW 399
            .||||||..|:.||.|.:..|..|:.....:|.||.|:.:|:.::..|:|||||.|..|.:..:|
Mouse   326 INELDKLQSLQALSCTRNPLSKADKAEEIIIAKIAQLRTLNRCQILPEERRGAELDYRKAFGNEW 390

  Fly   400 MQATQGG---TDSLR---EFCRRHRTYPLLVKKYGSPADFVPRSQ-----AKQSNLINVSIRHQL 453
            .:|  ||   .|..|   .|...|..|.||..|||:|.|...::|     .||...:.:...:|.
Mouse   391 RKA--GGHPDPDKNRPNAAFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKKQLLTLKIKCSNQP 453

  Fly   454 TGETWEKKVPRMITVQTLQGLVMKRFRLSGDVPQLCYVDALHPDLVVPLDNNAKTLDFYSVQEHD 518
            ..:..||::|..:|||.::||:.:..::......|.|..:..|...:.|:|:.:.|.||||:..|
Mouse   454 ERQILEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESSKMPGREIELENDLQPLQFYSVENGD 518

  Fly   519 TVLVQ 523
            .:||:
Mouse   519 CLLVR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbce	NP_610197.2	CAP_GLY	14..79	CDD:214997	31/64 (48%)
		LRR	<131..376	CDD:443914	74/248 (30%)
		leucine-rich repeat	158..183	CDD:275380	9/24 (38%)
		leucine-rich repeat	184..211	CDD:275380	10/26 (38%)
		leucine-rich repeat	212..238	CDD:275380	10/25 (40%)
		leucine-rich repeat	239..262	CDD:275380	4/22 (18%)
		leucine-rich repeat	263..287	CDD:275380	6/23 (26%)
		leucine-rich repeat	288..317	CDD:275380	8/28 (29%)
		leucine-rich repeat	318..343	CDD:275380	11/24 (46%)
		Ubl_TBCE	443..523	CDD:340564	21/79 (27%)
Tbce	NP_848027.1	CAP_GLY	10..75	CDD:214997	31/64 (48%)
		leucine-rich repeat	129..154	CDD:275380	5/28 (18%)
		LRR	<150..>346	CDD:443914	61/195 (31%)
		LRR 1	154..175		6/20 (30%)
		leucine-rich repeat	155..180	CDD:275380	9/24 (38%)
		LRR 2	180..201		8/20 (40%)
		leucine-rich repeat	181..206	CDD:275380	8/24 (33%)
		LRR 3	206..227		6/20 (30%)
		leucine-rich repeat	207..228	CDD:275380	7/20 (35%)
		LRR 4	231..253		6/21 (29%)
		leucine-rich repeat	232..254	CDD:275380	5/21 (24%)
		LRR 5	254..275		4/20 (20%)
		leucine-rich repeat	255..279	CDD:275380	5/23 (22%)
		LRR 6	279..300		5/20 (25%)
		leucine-rich repeat	280..309	CDD:275380	8/28 (29%)
		LRR 7	309..330		6/20 (30%)
		Ubl_TBCE	441..523	CDD:340564	22/79 (28%)