Protein Alignment Tbce and tip1

DIOPT Version :10

• Sequence 1: NP_610197.2
• Gene: Tbce / 35532
• FlyBaseID: FBgn0033055
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_593613.1
• Gene: tip1 / 2543044
• PomBaseID: SPAC3C7.12
• Length: 461
• Species: Schizosaccharomyces pombe
• Alignment Length: 517
• Identity: 107/517 - (20%)
• Similarity: 176/517 - (34%)
• Gaps: 199/517 - (38%)

  Fly    12 YPLGTRIKI--GDNYGTVRYVGEVSGHMGSWLGIEW--DDGLRGKHNGIVDGKRYFQTQTPTGGS 72
            :|||:.:::  |:. |.|||.|||....|.::|:|.  :....||:.|:|||:.||:|:
pombe     2 FPLGSVVEVITGER-GFVRYAGEVENRKGVYVGLELLPEFAEFGKNRGVVDGREYFKTK------ 59

  Fly    73 FIRPGKVGPCATLEDAARERYLNYDSSNVDESLIREAQASLQASLFEVVGMDKIARKQSKFEQLE 137
                                  |.:.:.:                  .|..|| .:..|......
pombe    60 ----------------------NNEKTGI------------------FVPFDK-CKLASSISSSP 83

  Fly   138 EVSVDQTPVNAAGYLKELTHLTTLNVSHTLIWNWEIVASIAQQLPSLTNLNLSSNRLVLPTSSQI 202
            ...:|.|..:.......::                  .::...:|.|||::.|||..:...||
pombe    84 SPKIDGTAASIGMGFPPMS------------------PNLQSSIPRLTNVSSSSNLSMNTISS-- 128

  Fly   203 TELEPSFRQL-KRINLRSCGFSDWKDVMHTALLWPNILSLGLQENSLGQLAEVDRTKIFKQLHEL 266
            |.|.|:.:.| |||          :|:::.            ::|...||.||..|  ..||..|
pombe   129 TALTPTEKILQKRI----------EDLLYE------------RQNHQQQLEEVLAT--VDQLQSL 169

  Fly   267 DLHRTNIMD-FDQVTKLGNLTTLRLLNIMENGIEEIKLPDCDSQEKLNIFVSLEQLNLLHN-PIW 329
               .||..| .|:|.:|....||:     |..|::::  :..||.:.....::|.|....| .|.
pombe   170 ---VTNFNDQQDEVDELRERITLK-----EERIQQMR--NEASQRRFEFKTTIECLEESSNRAIE 224

  Fly   330 NEADAFNELDKLPQLKRLSKTPHLKSNFDEMFSKAVASIASLQFINKAEVTAEQRRGAEYDIWKK 394
            ...:...||:  .||:.....   ||..|.:||                  .:|.|        .
pombe   225 TYENRIAELE--AQLEMYMSG---KSEDDLLFS------------------LQQER--------D 258

  Fly   395 YALDWMQATQGGTDSLREFCRRHRTYPLLVKKYGSPADFVPRSQAKQSNLINVSIRHQ------L 453
            |||:.::..|...|:|.:                         |...|:..|..:.|.      |
pombe   259 YALNQVEILQERVDTLMK-------------------------QKANSSTANEKLSHMESSSPTL 298

  Fly   454 TGETWEKKVPRMITVQTLQGLVMKRFRLSGDVPQLCYVDALHPDLVVPLDNNAKTLDFYSVQ 515
            |..::|..               ||.:.|.|:|:      .||       ...:||:||.::
pombe   299 TNASFESP---------------KRGKGSNDLPE------NHP-------QRRQTLEFYEIE 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbce	NP_610197.2	CAP_GLY	14..79	CDD:214997	22/68 (32%)
		LRR	<131..376	CDD:443914	54/247 (22%)
		leucine-rich repeat	158..183	CDD:275380	0/24 (0%)
		leucine-rich repeat	184..211	CDD:275380	11/26 (42%)
		leucine-rich repeat	212..238	CDD:275380	5/26 (19%)
		leucine-rich repeat	239..262	CDD:275380	6/22 (27%)
		leucine-rich repeat	263..287	CDD:275380	8/24 (33%)
		leucine-rich repeat	288..317	CDD:275380	5/28 (18%)
		leucine-rich repeat	318..343	CDD:275380	6/25 (24%)
		Ubl_TBCE	443..523	CDD:340564	16/79 (20%)
tip1	NP_593613.1	CAP_GLY	4..74	CDD:214997	26/117 (22%)
		SMC_prok_B	<142..399	CDD:274008	62/309 (20%)