DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14591 and tmem164

DIOPT Version :9

Sequence 1:	NP_001188864.1	Gene:	CG14591 / 35531	FlyBaseID:	FBgn0033054	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001072561.1	Gene:	tmem164 / 780016	XenbaseID:	XB-GENE-961759	Length:	283	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	109/273 - (39%)
Similarity:	156/273 - (57%)	Gaps:	25/273 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DWAVGGISDEIPRTTGPECINYMTDRRRWLETILL---SALFIFIMHR--------SWQRLAPIK 57
            ||..||:...|....|.||.:::...:|.||:::|   |.|.|.:..|        .|:
Frog     6 DWLYGGVDPNIAGNGGAECASFLPPGQRLLESLVLLIVSLLEIGVSLRKILRGRAGEWE------ 64

  Fly    58 LPPPHEIQKPHSPTRLFLLIALSMIFGIEMGFKLSGQSMIFALNPCHVQSCLQIYLLAAKPTKTT 122
             |......:..|..:..||:|:.:.||:|:|||.:.:::|:.||||||.:.|||:|||..|.|..
Frog    65 -PSGTPAVRCESLGKNLLLVAMCLTFGVEVGFKFATKTVIYLLNPCHVVTMLQIFLLACPPCKLA 128

  Fly   123 TALFRIQMSNLNGPFLAFLFPEVEGRTYPFEQATYWIQHALLYIIPIYIIR-SGAYTVEDLSEFH 186
            |.:||:||..|||..||.:||.:..|..|||...|::||.:||::|.|::| .|.||.|.:|:|.
Frog   129 TIIFRLQMHMLNGALLALVFPVLNTRLLPFEVEVYYVQHVMLYVVPFYLLRKGGVYTPEPMSDFW 193

  Fly   187 WSHIGTAFMLFYHFILLSPLSIFTGINLDHMLCAAMSDPFQGSNYRIFACCHQALLCPLLSKGTV 251
            |:.:||..|.||||..|..|.:.|.:||::|||.|:||||.|..|||:|..||.|:..:..|..|
Frog   194 WAILGTGLMFFYHFSFLQILGLVTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTLIHGKLIV 258

  Fly   252 VLFGRRNRSSSGL 264
            .||      |.||
Frog   259 FLF------SCGL 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14591	NP_001188864.1	TMEM164	3..252	CDD:291474	103/259 (40%)
tmem164	NP_001072561.1	TMEM164	6..259	CDD:317245	103/259 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3056
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12985
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3667
OMA	1	1.010	-	-		QHG58735
OrthoDB	1	1.010	-	-		D1509337at2759
OrthoFinder	1	1.000	-	-		FOG0006231
OrthoInspector	1	1.000	-	-		oto103143
Panther	1	1.100	-	-	LDO	PTHR20948
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2989
SonicParanoid	1	1.000	-	-		X4512
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110