Protein Alignment Strica and Casp8

DIOPT Version :10

• Sequence 1: NP_610193.1
• Gene: Strica / 35528
• FlyBaseID: FBgn0033051
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_071613.1
• Gene: Casp8 / 64044
• RGDID: 620945
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 79/299 - (26%)
• Similarity: 125/299 - (41%)
• Gaps: 52/299 - (17%)

  Fly   271 LGSSGGTK------PKVTAVAQSQ-DAQGTISTSLGISKSSLTKNKLKPARVY--IFNHERFDNK 326
            :.:.||.:      .:||...|.. |:.|. ..|..::..::.:.|.|| |.|  |||:..|...
  Rat   187 MSTEGGEELPVSVLDEVTIKMQDMWDSPGE-QESESLNSDNVYQMKSKP-RGYCLIFNNNNFSKA 249

  Fly   327 NE---------FRKGSAQDVKVLRATFEQLKCKVEVITDATLVTIKKTVRMLQTKDFEDKSALVL 382
            .|         .|||:..|.:.|..||::|..::...:|.|...|.:.:...|:||.:.|...:.
  Rat   250 REDIPKLSNMRDRKGTNYDEEALSKTFKELHFEIVSFSDCTASQIHEVLVSYQSKDHKGKDCFIC 314

  Fly   383 VILSHGTRHDQIAAKDDDYSLDD-DVVFPILRNRTLKDKPKLIFVQACKGDCQLGGFMTDAAQP- 445
            .|||||.:.........:.|:.: ...|...:..:|..|||:.|:|||:|:    .|......|
  Rat   315 CILSHGDKGIVYGTDGKEASIYELTSYFTGSKCPSLAGKPKIFFIQACQGN----NFQKAVPVPD 375

  Fly   446 ------------------NGSPNE--ILKCYSTYEGFVSFRTED-GTPFIQTLCEAL-NRSGKTS 488
                              |..|:|  .|...:|.:..||:|... ||.:||:||::| .|..:..
  Rat   376 ETGLEQEHVLEEDSSSYKNYIPDEADFLLGMATVKNCVSYRDPTRGTWYIQSLCQSLRERCPRGE 440

  Fly   489 DIDTIMMNVRQVVKMQSKDR----QIPSVTSTLTSKYVF 523
            ||.:|:..|...|..:...|    |:|....||..|..|
  Rat   441 DILSILTGVNYDVSNKDNPRNMGKQMPQPIFTLRKKLFF 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Strica	NP_610193.1	CASc	311..523	CDD:444667	69/250 (28%)
Casp8	NP_071613.1	DED_Caspase_8_r1	3..84	CDD:260041
		DD	98..179	CDD:472698
		CASc	227..480	CDD:237997	71/258 (28%)