DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Strica and caspbl

DIOPT Version :9

Sequence 1:	NP_001260718.1	Gene:	Strica / 35528	FlyBaseID:	FBgn0033051	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001139064.1	Gene:	caspbl / 566185	ZFINID:	ZDB-GENE-090311-53	Length:	409	Species:	Danio rerio

Alignment Length:	264	Identity:	66/264 - (25%)
Similarity:	113/264 - (42%)	Gaps:	44/264 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 QGTISTSLGISKSSLTKNKLKPARVYIFNHERFDNKNEFRKGSAQDVKVLRATFEQLKCKVEVIT 355
            |.|:|....:|::.      :.....:..:..|.||.:.|.|:.:|.:.:....:.|...|....
Zfish   156 QNTLSIYTPVSRTQ------RKGLALLITNILFANKQDDRAGAERDEENMEWLLKNLNFMVIKYR 214

  Fly   356 DATLVTIKKTVRMLQTK-DFEDKSALVLVILSHGTR-----------HDQIAAKDDDYSLDDDVV 408
            :.|...|.:.|:....: :.:|..:..:||:|||.|           ::.:..::|.|.::|  .
Zfish   215 NLTGNEISRAVQDFSRRHEHQDADSTFVVIMSHGDRIQNKDAILGVNYNWLQNRNDVYFVED--T 277

  Fly   409 FPILRN---RTLKDKPKLIFVQACKGDCQLGGFMTDAAQPNGSPNEILK-----CY-STYEGFVS 464
            |..|.:   ..|.||||:|.:|||:|. ||||.......|. |.:.:.|     |: ||....|:
Zfish   278 FSHLNSVNCPALIDKPKVILIQACRGG-QLGGVPVKDCVPE-SDSWVHKEKDFVCFMSTMPDVVA 340

  Fly   465 FRTE-DGTPFIQTLCEALNRSGKTSDIDTIMMNVRQVVKMQSKDRQ-------IPSV--TSTLTS 519
            :|.| .|:.||..:.:....|...   |.||...|:|.....||.:       :|.:  ||.:..
Zfish   341 YRDEVKGSYFISYIVDVFCSSACK---DHIMELFRKVAARMEKDERFRRQAKLLPCIERTSLVKK 402

  Fly   520 KYVF 523
            .|:|
Zfish   403 FYLF 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Strica	NP_001260718.1	CASc	311..523	CDD:294037	61/242 (25%)
caspbl	NP_001139064.1	Pyrin_ASC-like	5..84	CDD:260033
caspbl	NP_001139064.1	CASc	167..406	CDD:237997	61/251 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910