DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Strica and cflara

DIOPT Version :9

Sequence 1:	NP_001260718.1	Gene:	Strica / 35528	FlyBaseID:	FBgn0033051	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001300701.1	Gene:	cflara / 373114	ZFINID:	ZDB-GENE-030826-3	Length:	461	Species:	Danio rerio

Alignment Length:	206	Identity:	44/206 - (21%)
Similarity:	76/206 - (36%)	Gaps:	68/206 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 DVKVLRATFEQLKCKVEVITDATLVTIKKTVRMLQTKDFEDKS---------ALVLVILSHGTRH 391
            |.::|:.|||.|..||   ...:|:.:|:|.::|     ||.|         ..|..::|.||..
Zfish   260 DGEMLKHTFECLGFKV---VFHSLLGLKETQKVL-----EDLSLNRILQRVRCFVCCLISRGTNT 316

  Fly   392 DQIAAKDDDYSLDDDVVFPILRNRTLKDK---------PKLIFVQACKGDCQLGGFMTDAAQPNG 447
            ..:|...:...::            |||.         ||:.|.|..:        :|:|.....
Zfish   317 HLLATDSNRLGIN------------LKDLKQLFNATKCPKIFFTQLYR--------ITEAPVMPS 361

  Fly   448 SPNEIL--------KCYSTYEGFVSFRTEDGTPFIQTLCEA----LNRSGKTSDIDTIMMNVRQV 500
            ..:|.|        :|.:|  |.|....:    .:.::|.|    |..||..|    :.:|....
Zfish   362 MDDEYLETDAPASRQCSNT--GSVPMPAD----VLWSVCTAEVKLLEESGHQS----VYLNALNN 416

  Fly   501 VKMQSKDRQIP 511
            ..::..:|.:|
Zfish   417 ALLKGHERNVP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Strica	NP_001260718.1	CASc	311..523	CDD:294037	44/206 (21%)
cflara	NP_001300701.1	DED	8..87	CDD:307481
		DED_c-FLIP_r2	100..180	CDD:260046
		CASc	241..461	CDD:320727	44/206 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900