DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Strica and Casp14

DIOPT Version :9

Sequence 1:	NP_001260718.1	Gene:	Strica / 35528	FlyBaseID:	FBgn0033051	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001178705.1	Gene:	Casp14 / 299587	RGDID:	1311781	Length:	246	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	63/240 - (26%)
Similarity:	111/240 - (46%)	Gaps:	51/240 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 ERFDNK----------NEFRKGSAQDVKVLRATFEQLKCKVEVITDAT-------LVTIKKTVRM 368
            ||:|..          .:.|:||..|:..|...|:.||.:..:..|.|       :...::|:..
  Rat    14 ERYDMSGARLALTLCVTKAREGSEVDMDALERMFQYLKFESTMKRDPTAQQFLDDMDEFQQTIEN 78

  Fly   369 LQTKDFEDKSALVLVILSHGTRHDQIAAKDDD---YSLDDDVVFPILRN---RTLKDKPKLIFVQ 427
            .:    |..|...:|:::||   ::...|.:|   ..|:|  :|.:|.|   :.|:.|||:..:|
  Rat    79 WK----EPVSCAFVVLMAHG---EEGFLKGEDGNMVRLED--LFEVLNNKNCKALRGKPKVYIIQ 134

  Fly   428 ACKGDC-----QLGGFMTDAAQPNGSP-----NEILKCYSTYEGFVSFR-TEDGTPFIQTLCEA- 480
            ||:|:.     :|.|......:....|     .:::..|||.|||:|:| .:.|:.|||||.:.
  Rat   135 ACRGEHRDPGEELPGDELAVIKKKNPPTIPTYTDMIHIYSTVEGFLSYRHDQKGSGFIQTLTDVF 199

  Fly   481 LNRSGKTS----DIDTIMMNVRQVVKMQSKDRQI-PSVTSTLTSK 520
            :::.|..:    :|..:|.|..  |..:.|.|:: |.:.|||..|
  Rat   200 IHKKGSITELLEEITRLMANTE--VMQEGKPRKVNPEIQSTLRKK 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Strica	NP_001260718.1	CASc	311..523	CDD:294037	63/240 (26%)
Casp14	NP_001178705.1	CASc	10..246	CDD:237997	63/240 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010