DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Strica and Cflar

DIOPT Version :9

Sequence 1:	NP_001260718.1	Gene:	Strica / 35528	FlyBaseID:	FBgn0033051	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001029036.1	Gene:	Cflar / 117279	RGDID:	620847	Length:	480	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	53/227 - (23%)
Similarity:	93/227 - (40%)	Gaps:	58/227 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 DVKVLRATFEQLKCKVEVITDATLVTIKKTVR----MLQTKDFEDKSALVLVILSHGTRH----- 391
            |.:.||.||..|..:|:.....:...|.:.||    |.|.:|::   :.|.|::|.|...
  Rat   268 DTEYLRETFTSLGYRVQPFLFPSSHEITQIVRRFSNMTQHQDYD---SFVCVLVSRGGSQSMMGV 329

  Fly   392 DQIAAKDDDYSLDD--DV----VFPILRNRTLKDKPKLIFVQACK----GDCQLGGFMTDAAQPN 446
            ||:.:   .:||::  |:    :.|.||.     ||||.|:|..:    ...::.|    .|..|
  Rat   330 DQVYS---GFSLENVKDMFKGDMCPSLRG-----KPKLFFIQNYEALEDNSLEVDG----PAIKN 382

  Fly   447 GSPNEILKCYST----YEGFVSFRTEDG----------TPFIQTLCEALNRSGKTSDIDTIMMNV 497
            .:...:...:.|    .:.|.|..|.|.          :.::|.|.:.|.:..|.|.:|   ::|
  Rat   383 VNSRHLHPRHCTTHPDADIFWSLCTADVSRLEQPSSSLSVYLQKLSQLLEQGRKRSLVD---LHV 444

  Fly   498 RQVVK-------MQSKDRQIPSVTSTLTSKYV 522
            ..:.|       :.||::...|:..||..|.:
  Rat   445 ELMDKVYAWNSNVPSKEKYYLSLQHTLRKKLI 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Strica	NP_001260718.1	CASc	311..523	CDD:294037	53/227 (23%)
Cflar	NP_001029036.1	DED_c-FLIP_r1	6..85	CDD:260044
		DED_c-FLIP_r2	96..176	CDD:260046
		CASc	249..479	CDD:412128	53/227 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900