DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Strica and si:ch211-195h23.3

DIOPT Version :9

Sequence 1:	NP_001260718.1	Gene:	Strica / 35528	FlyBaseID:	FBgn0033051	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_021334238.1	Gene:	si:ch211-195h23.3 / 100170660	ZFINID:	ZDB-GENE-070912-174	Length:	1001	Species:	Danio rerio

Alignment Length:	217	Identity:	37/217 - (17%)
Similarity:	68/217 - (31%)	Gaps:	81/217 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 KTTSSTSSSSA-------SSITSPPKPSSSVSSISSIFKSAPKQVDKPLSSTA---TPKPFISLG 272
            |...:..|.||       .|:.|||:..||..              :|.|.:|   ||:...::.
Zfish   582 KIVQADESLSAVEQEKEGKSLGSPPRAESSTG--------------QPTSESAEEFTPELIQTVD 632

  Fly   273 S-------------SGGTKPKVTAVAQSQDAQGTISTSLGISKSSLTKNKLKPARVYIFNHERFD 324
            .             :|..:..:|::....|.:|.:.                 .||..::....|
Zfish   633 EDKHKNTYRFVCPHAGQFQCSLTSLVFVMDGEGELL-----------------YRVVSWDPRLLD 680

  Fly   325 NKNEFR-KGSAQDVKVLRATFEQL---KCKV--------------------EVITDATLVTIKKT 365
            ...:.: .|...|||....:..:|   .|::                    |::..   :|:.:|
Zfish   681 GLGQMQPAGPLYDVKCFNGSISKLHLPHCEIFSEGDNMDGLAVAHFTGGNMEIVQP---ITVTET 742

  Fly   366 VRMLQTKDFEDKSALVLVILSH 387
            ..|:..:|......|.:.|.||
Zfish   743 HVMIDIRDLSLFGLLWMKIFSH 764

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Strica	NP_001260718.1	CASc	311..523	CDD:294037	18/101 (18%)
si:ch211-195h23.3	XP_021334238.1	P-loop_NTPase	51..307	CDD:328724
		GBP_C	315..602	CDD:293879	4/19 (21%)
		coiled coil	573..584	CDD:293879	1/1 (100%)
		coiled coil	593..602	CDD:293879	0/8 (0%)
		FIIND	645..885	CDD:316110	22/140 (16%)
		CARD_ASC_NALP1	910..991	CDD:260039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900