Protein Alignment Pngl and Ngly1

DIOPT Version :9

• Sequence 1: NP_610192.1
• Gene: Pngl / 35527
• FlyBaseID: FBgn0033050
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_038949377.1
• Gene: Ngly1 / 361014
• RGDID: 1308518
• Length: 651
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 218/642 - (33%)
• Similarity: 330/642 - (51%)
• Gaps: 85/642 - (13%)

  Fly    30 EAYLEAVRILLVLLENILAQPENSMFRTIRQENKAIKEKLLSLPGCERLLEAIGFVRAPSSNAYT 94
            |.:|||.::||...:|||..|.:..:|:||..|.|...:||.:.|....|..:||....:...:
  Rat    26 ETFLEASKLLLTYADNILRNPSDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIF- 89

  Fly    95 LPTEVSLQQVKKYRDALSERRTAWLNGTVSK-----------------------------SPPQQ 130
             |.:.|::|::|.||.::..|.:.|:|:..|                             .|.|.
  Rat    90 -PKKASVEQLQKIRDLIAVERRSRLDGSSQKVEFSQHPAAVRLPAEQPEDPTGLMQHSGNQPGQP 153

  Fly   131 STTSTTPLFIKPSVEYRHRIAFPRVLRTNNNFLQSLELYSDAVMQYEDNLLLATGRTLIPVEELT 195
            .:..:.||.:..|..:       :||::|   :|.::||.:.|:|.:       ....|||.||.
  Rat   154 LSLPSAPLVVGDSTIF-------KVLQSN---IQHVQLYENPVLQEK-------ALACIPVNELK 201

  Fly   196 EMASEKLIDIQDQIASGERQEKEPCVRDLLLVELVNWFNTQFFQWVNNIPCRVCG----SEESRL 256
            ..:.|||...: ::..|.:...|    |.||:||::||..:||.||||:.|..||    |.:..|
  Rat   202 RKSQEKLFRAR-KLDKGTKVSDE----DFLLLELLHWFKEEFFHWVNNVVCSRCGRETRSRDEAL 261

  Fly   257 RRTERE---GDIRVEVTVC--CGQESKFYRYNDISQLLVSRKGRCGEYANCFTFLCRALDYDARI 316
            ...:.|   |...||...|  |...::|.|||:..:||.:|.|||||:|||||..||||.::||.
  Rat   262 PPNDDELKWGAKNVEDHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARY 326

  Fly   317 VHSHFDHVWTEVYSEAQMRWLHVDPSENVIDSPLMYQHGWKRHIDYILAYSRDDIQDVTWRYTND 381
            |..:.|||||||||.:|.||||.|..|:|.|.||:|:.||.:.:.||:|:|:|::.||||||:..
  Rat   327 VWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYIIAFSKDEVVDVTWRYSCK 391

  Fly   382 HQKILHLRKLCGEKEMVQTLDAIRAKRRQNCTADRKLFLSQRNMYEVIGLTLERKPTENELKGRS 446
            |::::..|....|:.:.:|::.:..:|:...:..|:..|.||.:.|::.....:.|...||.||.
  Rat   392 HEEVMSRRTKVKEELLRETINGLNKQRQLLLSESRRKELLQRIIVELVEFISPKTPRPGELGGRV 456

  Fly   447 SGSLSWRQSRGEHTF-TNIFVFNLSATELQKRQLNVRYSCATDTYERYAKEGEHITILDSYKTWQ 510
            ||||:||.:|||... ....:|..|..|...:|.::||....|.|.|.:....:|:      .|:
  Rat   457 SGSLAWRVARGETCLERKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNNANIS------GWE 515

  Fly   511 KAQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSKTNLKVKSYNLVFETKTFGDGKISV 575
            ...:..::||||||:||.|.||||.|.:....|:|.|:.....|||.:.::...:::|..|  ||
  Rat   516 NGVWKMESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDNVSIRTSSQSFETG--SV 578

  Fly   576 TVDATDGSASVE--------------NATGFKIVAKLTGGKGDVAWQHTQLFRQSLN 618
            ........|.|.              .||...:.|:|:.|.||||||||||||||||
  Rat   579 RWKLRSEMAQVNLLGDRNLRSYDDFCGATEVTLEAELSRGDGDVAWQHTQLFRQSLN 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pngl	NP_610192.1	PUB	30..107	CDD:286494	24/76 (32%)
		CitX	98..>185	CDD:294885	22/115 (19%)
		Transglut_core	<278..341	CDD:280085	38/62 (61%)
		YebA	<282..378	CDD:224224	54/95 (57%)
		Rad4	<325..>383	CDD:281786	31/57 (54%)
		PAW	444..630	CDD:282564	69/190 (36%)
Ngly1	XP_038949377.1	PUB_PNGase	19..109	CDD:198417	27/84 (32%)
		Transglut_core	272..351	CDD:376628	42/78 (54%)
		sm_acid_XPC-like	<335..>402	CDD:415878	33/66 (50%)
		PAW	454..648	CDD:398412	69/190 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337432
Domainoid	1	1.000	107	1.000	Domainoid score	I6402
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10117
Inparanoid	1	1.050	343	1.000	Inparanoid score	I2266
OMA	1	1.010	-	-		QHG49076
OrthoDB	1	1.010	-	-		D522988at33208
OrthoFinder	1	1.000	-	-		FOG0004891
OrthoInspector	1	1.000	-	-		oto97646
orthoMCL	1	0.900	-	-		OOG6_103952
Panther	1	1.100	-	-	LDO	PTHR12143
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3448
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910