DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pngl and W04G5.9

DIOPT Version :9

Sequence 1:	NP_610192.1	Gene:	Pngl / 35527	FlyBaseID:	FBgn0033050	Length:	631	Species:	Drosophila melanogaster
Sequence 2:	NP_001364612.1	Gene:	W04G5.9 / 189204	WormBaseID:	WBGene00012269	Length:	407	Species:	Caenorhabditis elegans

Alignment Length:	159	Identity:	35/159 - (22%)
Similarity:	52/159 - (32%)	Gaps:	46/159 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   479 LNVRYSCATDTYERYAKEGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCGEI 543
            |:..|....|.|.:..:.|....:.|           .|||.|..:.:....|...::..|.|.|
Worm   258 LDFEYDIVKDKYSQSPENGLFSQVYD-----------VKNIRRIRDTNTNEVYFGLVDGADHGTI 311

  Fly   544 AWTFDFSKTNLKV------------KSYN--------LVFETKTFGDGKISVTVDATDGSASVEN 588
            :|.||....|.|:            .|||        :..|........::...|...|..:|
Worm   312 SWRFDKDLNNNKIGRVDIEVRDDEEYSYNGKAIATFCIADECWIIRRNSVTSIYDTKHGQINV-- 374

  Fly   589 ATGFKIVAKLTGGKGDVAWQHTQLFRQSL 617
                  :..||||       ..|:||:||
Worm   375 ------IFILTGG-------DAQIFRRSL 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pngl	NP_610192.1	PUB	30..107	CDD:286494
		CitX	98..>185	CDD:294885
		Transglut_core	<278..341	CDD:280085
		YebA	<282..378	CDD:224224
		Rad4	<325..>383	CDD:281786
		PAW	444..630	CDD:282564	35/159 (22%)
W04G5.9	NP_001364612.1	PAW	252..339	CDD:214745	19/91 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157785
Domainoid	1	1.000	61	1.000	Domainoid score	I6914
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930