DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pngl and W04G5.5

DIOPT Version :9

Sequence 1:	NP_610192.1	Gene:	Pngl / 35527	FlyBaseID:	FBgn0033050	Length:	631	Species:	Drosophila melanogaster
Sequence 2:	NP_492967.4	Gene:	W04G5.5 / 189201	WormBaseID:	WBGene00012266	Length:	412	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	42/223 - (18%)
Similarity:	69/223 - (30%)	Gaps:	69/223 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   429 IGLT-------LERKPTENELKGRSSGSLSWRQSRGEHTFTNIFVFNLSATELQKRQLNVRYSCA 486
            :|||       |:..|..|    .|..|:....:.||                  ..:...|...
Worm    53 LGLTELLFDERLQESPPHN----FSGKSIELTLNPGE------------------EYIKFTYDVI 95

  Fly   487 TDTYERYAKEGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSK 551
            .|.|....|:|           :....:..:|:.|..|.|..|.:|.::...|...|:|.||...
Worm    96 NDVYSHSPKKG-----------FMAQAYYMENMKRCEEPDHIMVHLCKISIDDEATISWHFDLKS 149

  Fly   552 TNLKVKSYNL------VFETKTFGDGKISV----TVDATDGSASVEN--ATGFKIVAKLTGGKGD 604
            ....:|...:      .|...:....|..:    .|.|.:....::|  .:.|.:...|.|
Worm   150 IERPIKKVEVRMGGFAEFSGSSLARAKACIGNVCRVLANNNIERIDNPDISIFTVTVMLLG---- 210

  Fly   605 VAWQHTQLFRQSLNS---------RDYP 623
                ::|:||.:.|.         |.||
Worm   211 ----NSQIFRTNWNKGTEIESFLVRIYP 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pngl	NP_610192.1	PUB	30..107	CDD:286494
		CitX	98..>185	CDD:294885
		Transglut_core	<278..341	CDD:280085
		YebA	<282..378	CDD:224224
		Rad4	<325..>383	CDD:281786
		PAW	444..630	CDD:282564	36/201 (18%)
W04G5.5	NP_492967.4	PAW	82..169	CDD:214745	20/115 (17%)
W04G5.5	NP_492967.4	PAW	255..342	CDD:214745
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157790
Domainoid	1	1.000	61	1.000	Domainoid score	I6914
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522988at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940