Protein Alignment Pngl and png-1

DIOPT Version :9

• Sequence 1: NP_610192.1
• Gene: Pngl / 35527
• FlyBaseID: FBgn0033050
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_492913.1
• Gene: png-1 / 173028
• WormBaseID: WBGene00010160
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 167/591 - (28%)
• Similarity: 256/591 - (43%)
• Gaps: 113/591 - (19%)

  Fly    91 NAYTLPTEVSL---QQVKKYRDALSERRTAWLNGTVSKSPPQQSTTSTTPLFIKPSVEYRHRIAF 152
            |...:||.:.|   |||...|.|..:.....:....|.:|...:..|.
 Worm    72 NISAMPTFIFLKNRQQVDMVRGANQQAIAEKIRQHYSPTPANPNAASD----------------- 119

  Fly   153 PRVLRTNNNFLQSLELYSDAVMQYEDNLLLATGRTLIPVEELTEMASEKLIDIQDQIASGERQEK 217
                 :...||:.....|:....|:|.:..|..|:::| |||...|          :..|.|.||
 Worm   120 -----SEKRFLEQFVKCSNVPRSYQDEVFKALARSVMP-EELVGRA----------MTEGPRDEK 168

  Fly   218 EPCVRDLLLVELVNWFNTQFFQWVNNIPCRVC-------GSEESRLRRTEREGDI-RVEVTVC-- 272
                  .:|.:|::||.||||.|.:...|..|       |.:.:..|..::||.. ||||.:|
 Worm   169 ------AILKDLLHWFKTQFFTWFDRPTCPKCTLKCSTDGLQGTPTREEQKEGGASRVEVYICDG 227

  Fly   273 CGQESKFYRYNDISQLLVSRKGRCGEYANCFTFLCRALDYDARIVHSHFDHVWTEVYSEAQMRWL 337
            |..|.:|.|||:.::||.:|.|||||:||||..|..||:.::|.::...||||.|||..|:.||.
 Worm   228 CNTEMRFPRYNNPAKLLQTRTGRCGEWANCFGLLLAALNLESRFIYDTTDHVWNEVYLLAEQRWC 292

  Fly   338 HVDPSENVIDSPLMYQHGWKRHIDYILAYSRDDIQDVTWRYTNDHQKILHLRKLCGEKEMVQTLD 402
            ||||.||.:|.||:|..||.:.:.|.:.|..|.:.||||||..|.:|::..|....:......|.
 Worm   293 HVDPCENTMDRPLLYTRGWGKTLGYCIGYGSDHVVDVTWRYIWDSKKLVTQRNEVRQPVFENFLS 357

  Fly   403 AIRAKRRQNCTADRKLFLSQRNMYEVIGLTLERKPTE--------NELKGRSSGSLSWRQSRGEH 459
            .:.:::.:..|..||..|:.|.:.|::.:..:.....        ::|.||.:||..||:.|||
 Worm   358 KLNSRQAEGQTEPRKRELAVRRVCELMEMMAQEAKNHKIGWEKIGDDLGGRITGSEEWRRERGE- 421

  Fly   460 TFTNIFVFNLSATEL-------------QKRQLNVRYSCATDTYERYAKEGEHITILDSYKTWQK 511
                   ...|..:|             .:..|...|...||||.:..:.|           :..
 Worm   422 -------LGESGPKLLAEPIKLAPPTGPAQNYLEFNYDVITDTYSQPPEIG-----------FSA 468

  Fly   512 AQFSSKNIFRKVERDWKMAYLARLEDTDCGEIAWTFDFSKTNLKVKSYNL------VFE------ 564
            ..|..:|:.|..|.||.|.||.|......|.|:|.||.......::...:      .||
 Worm   469 QAFELENVQRVEETDWNMTYLCRKRGDAPGNISWHFDLKSLKKSIEKIEIRMAGIQKFEKGKAMA 533

  Fly   565 TKTFGDGKISVTVDATDGSASVE---NATGFKIVAKLTGGKGDVAWQHTQLFRQSL----NSRDY 622
            ....||..:.:.:|.:  :.::|   ||...||.|.|:||:|.:.:|..|:||..|    .:|..
 Worm   534 IACLGDSCMRLPIDCS--ALTIEDPKNAEILKITATLSGGEGAIGFQQAQIFRTELKRGGGARTE 596

  Fly   623 PFDLQV 628
            .|.:::
 Worm   597 SFSVKI 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pngl	NP_610192.1	PUB	30..107	CDD:286494	7/18 (39%)
		CitX	98..>185	CDD:294885	15/89 (17%)
		Transglut_core	<278..341	CDD:280085	32/62 (52%)
		YebA	<282..378	CDD:224224	47/95 (49%)
		Rad4	<325..>383	CDD:281786	29/57 (51%)
		PAW	444..630	CDD:282564	55/217 (25%)
png-1	NP_492913.1	TRX_family	20..103	CDD:239245	9/30 (30%)
		Transglut_core	204..296	CDD:280085	42/91 (46%)
		YebA	<235..312	CDD:224224	40/76 (53%)
		PAW	407..604	CDD:299187	55/217 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157786
Domainoid	1	1.000	81	1.000	Domainoid score	I5492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10117
Inparanoid	1	1.050	227	1.000	Inparanoid score	I2223
Isobase	1	0.950	-	0	Normalized mean entropy	S984
OMA	1	1.010	-	-		QHG49076
OrthoDB	1	1.010	-	-		D522988at33208
OrthoFinder	1	1.000	-	-		FOG0004891
OrthoInspector	1	1.000	-	-		oto19343
orthoMCL	1	0.900	-	-		OOG6_103952
Panther	1	1.100	-	-	LDO	PTHR12143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3448
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.860