Protein Alignment Pngl and Pngl

DIOPT Version :10

• Sequence 1: NP_610192.1
• Gene: Pngl / 35527
• FlyBaseID: FBgn0033050
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_061504268.1
• Gene: Pngl / 1269792
• VectorBaseID: AGAMI1_002532
• Length: 680
• Species: Anopheles gambiae
• Alignment Length: 680
• Identity: 300/680 - (44%)
• Similarity: 404/680 - (59%)
• Gaps: 87/680 - (12%)

  Fly    25 ERGLKEAYLEAVRILLVLLENILAQPENSMFRTIRQENKAIKEKLLSLPGCERLLEAIGFVRAPS 89
            |...||||:.|...||.||:||:.:|:|:.:||:|.:|.:|:|||||:.|.::|:.|||||.  |
Mosquito    13 ESNPKEAYVVAAETLLRLLDNIIREPQNAKYRTVRIDNPSIREKLLSVEGMKQLMLAIGFVE--S 75

  Fly    90 SNAYTLPTEVSLQQVKKYRDALSERRTAWLNGTVSKSPPQQ-----------------------S 131
            :...|:|:.|.|..|::||:.|.||:      .:.|:||::                       :
Mosquito    76 NGTLTVPSNVLLANVRRYREFLYERK------ELVKNPPKEKDITPIGSVTCTESNSSTASAAVT 134

  Fly   132 TTSTTPL-------------------------------FIKPSVEYRHRIAFPRVLRTNNNFLQS 165
            |||||.:                               .||.|..:..||.||:|:..||..|:.
Mosquito   135 TTSTTNIPQEAATEKSKMVLQPSGSNATAGQQRTEALCVIKSSRPFLARIEFPKVIPGNNTLLRQ 199

  Fly   166 LELYSDAVMQYEDNLLLATGRTLIPVEELTEMASEKLIDIQDQIASGER--QEKEPCVRDLLLVE 228
            |||.||.||||||.||||:|.:|||::.||..|..||...|..:|:.|.  |.|||..:||||.|
Mosquito   200 LELLSDQVMQYEDELLLASGTSLIPIDTLTAKAKSKLTQWQRLLATSEATDQSKEPSEKDLLLEE 264

  Fly   229 LVNWFNTQFFQWVNNIPCRVCGSEESRLRRTEREGDIRVEVTVCCGQESKFYRYNDISQLLVSRK 293
            |..||..:||.|||.:||.|||:|:::|.|:..|..:||||..||||...||||||:.:||.:|:
Mosquito   265 LTAWFRAEFFTWVNALPCTVCGNEKTQLVRSTVEDGVRVEVYQCCGQLRHFYRYNDVEKLLQTRR 329

  Fly   294 GRCGEYANCFTFLCRALDYDARIVHSHFDHVWTEVYSEAQMRWLHVDPSENVIDSPLMYQHGWKR 358
            |||||:|||||||||.|.||||.|.|..|||||||:||.:.||:||||.|||:|:||||:|||::
Mosquito   330 GRCGEWANCFTFLCRCLGYDARYVFSTGDHVWTEVWSERRQRWIHVDPCENVLDAPLMYEHGWRK 394

  Fly   359 HIDYILAYSRDDIQDVTWRYTNDHQKILHLRK---LCGEKEMVQTLDAIRAKRRQ--NCTADRKL 418
            .|.|:..::|||:||||||||||||::|..|:   .|.|..::..:..:|.|||.  |||.::..
Mosquito   395 EITYVFGFARDDVQDVTWRYTNDHQRLLQRRRQGGACSEHALLDAIAKLRTKRRAGLNCTPEQMS 459

  Fly   419 FLSQRNMYEVIGLTLE--RKPTENELKGRSSGSLSWRQSRGEHTFTNIFVFNLSATELQKRQLNV 481
            .|.:|.:.|.:.|...  |.||..|.:|||||||.||..|||......::|..:..|:|.:|.|:
Mosquito   460 LLRKRTIDECLELLANAGRVPTAAEREGRSSGSLEWRLQRGEQQTNTRYMFIPTEEEVQAKQFNI 524

  Fly   482 RYSCATDTYERYAK-----EGEHITILDSYKTWQKAQFSSKNIFRKVERDWKMAYLARLEDTDCG 541
            ||.||||.|||:.|     ..|.||  :....|:..|:.|:|||||.|.||||.||||.|..|..
Mosquito   525 RYCCATDCYERFLKGASNRVNERIT--EKSNGWESRQYVSRNIFRKEELDWKMVYLARTEGIDEA 587

  Fly   542 EIAWTFDFSKTNLKVKSYNLVFETKTFGDGKISVTVDATDGS-----ASVENATGFKIVAKLTGG 601
            .|.|.||||...|:||...|.|..:|:...|:.:....:|||     :|:.....|.:.|:|:||
Mosquito   588 TIEWNFDFSVQGLRVKQIELRFGQETYEGAKVELYYIKSDGSQSQALSSLCECGKFTLQARLSGG 652

  Fly   602 KGDVAWQHTQLFRQSLNSRD-YPFDLQVQL 630
            |   :|||.||||||..:.| |||::.:.|
Mosquito   653 K---SWQHAQLFRQSKTATDEYPFEMNIVL 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pngl	NP_610192.1	PUB	29..109	CDD:462790	37/79 (47%)
		Transglut_core	<278..341	CDD:376628	43/62 (69%)
		Rad4	<325..>383	CDD:427539	38/57 (67%)
		PAW	444..630	CDD:461409	85/196 (43%)
Pngl	XP_061504268.1	None