DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act42A and ARP7

DIOPT Version :9

Sequence 1:	NP_523625.1	Gene:	Act42A / 35526	FlyBaseID:	FBgn0000043	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_015359.1	Gene:	ARP7 / 856146	SGDID:	S000006238	Length:	477	Species:	Saccharomyces cerevisiae

Alignment Length:	468	Identity:	95/468 - (20%)
Similarity:	180/468 - (38%)	Gaps:	126/468 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVG-----DEAQSKRG---I 65
            :|:.|||....|||:..:.|:.:.||...:...:|     |:.:...|     |.|..||.   :
Yeast     8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEG-----GEAEFIFGTYNMIDAAAEKRNGDEV 67

  Fly    66 LTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPK---ANREKMTQIMFET 127
            .||  ....|:..|||.:|..|.:.:..:|:|:|||.|:::|....|.|   |..|:..::.|:.
Yeast    68 YTL--VDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDK 130

  Fly   128 FNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLM- 191
            .|.|...:.|:.:....:.|:::..|:|.|....:..||.:|..:.:|::|....| |..|:.:
Yeast   131 LNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG-DFLDFQVH 194

  Fly   192 --------------------KILTERGYSFTT-------------------------------TA 205
                                |..|:..|..:|                               ..
Yeast   195 ERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAK 259

  Fly   206 EREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIG-NERFRCPESLFQPSFL- 268
            ::|.::.:.::|.|.||............:.|.|    |..:.:|:. .|.::..|.||:|..:
Yeast   260 QQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFK----PLNKTLTLDLKECYQFAEYLFKPQLIS 320

  Fly   269 -------------------------GMEA-----------------CGIHETTYNSIMKCDVDIR 291
                                     .|:|                 .|.:.:|.:|.......:.
Yeast   321 DKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVY 385

  Fly   292 KDLYANTVLSGGTTMYPGIADRMQKEITALAP----STMKIKIVAPPERKYSVWIGGSILASLST 352
            ..|..|.:::|.|::..|:..|:.||::...|    :|...:::.  :||...|:|...:|:|.:
Yeast   386 SLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMM--DRKIQGWLGALTMANLPS 448

  Fly   353 FQ-QMWISKQEYD 364
            :. ..|.||::|:
Yeast   449 WSLGKWYSKEDYE 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	PTZ00281	1..376	CDD:173506	95/468 (20%)
ARP7	NP_015359.1	COG5277	1..471	CDD:227602	95/468 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810