Protein Alignment Act42A and ACTRT3

DIOPT Version :10

• Sequence 1: NP_523625.1
• Gene: Act42A / 35526
• FlyBaseID: FBgn0000043
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_115876.3
• Gene: ACTRT3 / 84517
• HGNCID: 24022
• Length: 372
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 181/368 - (49%)
• Similarity: 264/368 - (71%)
• Gaps: 3/368 - (0%)

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 73
            :|:||||||.|||.||...|:.::|:|:||.:.|. ....|..:..|||:||..|..|.:.||:|
Human     8 VVIDNGSGMIKAGVAGCREPQFIYPNIIGRAKGQS-RAAQGGLELCVGDQAQDWRSSLFISYPVE 71

  Fly    74 HGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQ 138
            .|::|:|:|||.:|.|.:...|::.|.:.|||:||..|||.|||:::|::.||....||.|::||
Human    72 RGLITSWEDMEIMWKHIYDYNLKLKPCDGPVLITEPALNPLANRQQITEMFFEHLGVPAFYMSIQ 136

  Fly   139 AVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT 203
            |||:|:|:|.|||:||:||.||:.:|||:|||.|||.:.:|||||.|||:|||.::...|....:
Human   137 AVLALFAAGFTTGLVLNSGAGVTQSVPIFEGYCLPHGVQQLDLAGLDLTNYLMVLMKNHGIMLLS 201

  Fly   204 TAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFL 268
            .::|:||.||||..||||:::|:||  |.....|||.|:||||:||.:.::.|.|||:||.|..:
Human   202 ASDRKIVEDIKESFCYVAMNYEEEM--AKKPDCLEKVYQLPDGKVIQLHDQLFSCPEALFSPCHM 264

  Fly   269 GMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAP 333
            .:||.||.:..::||||||..:|...::|.:|:||:|.:||:..|:.|:|..:||:...::::||
Human   265 NLEAPGIDKICFSSIMKCDTGLRNSFFSNIILAGGSTSFPGLDKRLVKDIAKVAPANTAVQVIAP 329

  Fly   334 PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            ||||.|||:|||||||||.||.|||:..|:.|.||:|||::||
Human   330 PERKISVWMGGSILASLSAFQDMWITAAEFKEVGPNIVHQRCF 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	ASKHA_NBD_actin	7..371	CDD:466823	176/361 (49%)
ACTRT3	NP_115876.3	ASKHA_NBD_actin_Arp-T1-3	7..363	CDD:466848	174/357 (49%)