DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act42A and Actl9

DIOPT Version :9

Sequence 1:	NP_523625.1	Gene:	Act42A / 35526	FlyBaseID:	FBgn0000043	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_899105.2	Gene:	Actl9 / 69481	MGIID:	1916731	Length:	415	Species:	Mus musculus

Alignment Length:	375	Identity:	154/375 - (41%)
Similarity:	241/375 - (64%)	Gaps:	9/375 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVG-RPRHQGVMVGMGQKDSYVGDEAQSKRGILTL 68
            :..|:|:|.|:|.||.||||...|.....:|:| :|:.|... ...:.::::|:.|:| |..|.|
Mouse    47 KTGAVVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATK-DQSELETFIGEAARS-RPELRL 109

  Fly    69 KYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAM 133
            ..||.:|||.:|:..|.||.|...::|:||..|||:|.::.|.:|..||||:.::.||:.::||:
Mouse   110 VKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPAL 174

  Fly   134 YVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERG 198
            |||.|:|||:||.||..|:|:|:|.|||:|||:.:||.|||||.||||||..||.:|.::|...|
Mouse   175 YVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSG 239

  Fly   199 YSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLF 263
            :|. ...:.::|.:||...||:|.||::|.  |......::|.:||||:.:|:|.|.|:|||.||
Mouse   240 FSL-QQEDLDLVENIKHHYCYLAPDFQKEQ--ARPDEECKQSLKLPDGRTVTLGKELFQCPELLF 301

  Fly   264 QPSFL-GMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEIT-ALAPSTM 326
            .|..: |:...|:......|::|...::|..:..|.:|.||::::.|:..|.:.|:. :|:|..
Mouse   302 HPPEIPGLSPIGLPAMAEQSLLKVPQELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSPED- 365

  Fly   327 KIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            .:.::|.|.|..||||||||||||..||..|:.:::|:|.||.:|:|||:
Mouse   366 HVVVMAHPNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	PTZ00281	1..376	CDD:173506	153/373 (41%)
Actl9	NP_899105.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
Actl9	NP_899105.2	ACTIN	48..414	CDD:214592	152/371 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820