DRSC/TRiP Functional Genomics Resources

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Protein Alignment Act42A and Actl6a

DIOPT Version :10

Sequence 1:NP_523625.1 Gene:Act42A / 35526 FlyBaseID:FBgn0000043 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001034122.1 Gene:Actl6a / 361925 RGDID:1307747 Length:429 Species:Rattus norvegicus


Alignment Length:423 Identity:152/423 - (35%)
Similarity:227/423 - (53%) Gaps:54/423 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 EEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVG----RPRHQGVMVGMGQKDS------YVGDE 58
            :||.|||.|.||...:||:||:|.|:..||:.:|    |.....:|...|.|..      |:...
  Rat     9 DEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGVVLERDDGSTMMEIDGDKGKQGGPTYYIDTN 73

  Fly    59 A-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQ 122
            | :..|..:....|:::|:|.:||..:.|..||:...::.....||||::|||.|.:|.|||:|:
  Rat    74 ALRVPRESMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTE 138

  Fly   123 IMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHT--VPIYEGYALPHAILRLDLAGRD 185
            :|||.::.||.::...|||:.:|:||:||::|||  |.:||  :|:::||.|...|::..|||..
  Rat   139 LMFEHYSIPAFFLCKTAVLTAFANGRSTGLILDS--GATHTTAIPVHDGYVLQQGIVKSPLAGDF 201

  Fly   186 LTDYLMKILTERGYSFT---TTAEREIVRD-------IKEKL-------------CYVALDFEQE 227
            :|....::..|......   ..|.:|.||:       .||||             | |..||:..
  Rat   202 ITMQCRELFQEMNIELIPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNC-VIQDFQAS 265

  Fly   228 MATAASSSSLEK--------SYELPDGQVITIGNERFRCPESLFQPS----FLGMEACGIHETTY 280
            :...:.|:..|:        .||.|:|.....|.||.:.||.||.||    ..|....|:.....
  Rat   266 VLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTMLGVSHVVT 330

  Fly   281 NSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVA---PPERKYSVWI 342
            .|:..||:|||..||.:.:::||.|:.....||:.:|::...|.:|::|::|   ..||::|.||
  Rat   331 TSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWI 395

  Fly   343 GGSILASLSTFQQMWISKQEYDESGPSIVHRKC 375
            ||||||||.||||||||||||:|.|...|.|||
  Rat   396 GGSILASLGTFQQMWISKQEYEEGGKQCVERKC 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Act42ANP_523625.1 ASKHA_NBD_actin 7..371 CDD:466823 146/414 (35%)
Actl6aNP_001034122.1 ASKHA_NBD_Arp4_ACTL6-like 8..420 CDD:466846 147/413 (36%)

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