DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act42A and Actrt2

DIOPT Version :9

Sequence 1:	NP_523625.1	Gene:	Act42A / 35526	FlyBaseID:	FBgn0000043	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001013959.1	Gene:	Actrt2 / 298671	RGDID:	1359657	Length:	377	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	184/369 - (49%)
Similarity:	259/369 - (70%)	Gaps:	2/369 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPI 72
            :::.|||||:||||.:|:..||.|..|:||.|:.:....|..||..:||:||..|:..|.|:.||
  Rat    11 SVIFDNGSGLCKAGLSGEIGPRHVTSSVVGYPKFKASPTGACQKKYFVGEEALFKQETLRLQSPI 75

  Fly    73 EHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAI 137
            |.|::|:|||:||:|.|.|..||.|.|.|.|||:||..|||:.||||..::|||||..||.|::.
  Rat    76 ERGLITSWDDIEKLWRHLFEWELGVKPSERPVLMTEPSLNPRENREKTAEVMFETFEVPAFYLSD 140

  Fly   138 QAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT 202
            ||||:||:|...||:|:||||||:.||||:|||:||||:.:|.:||:|:|:.|.::|...|.:|.
  Rat   141 QAVLALYSSACVTGLVVDSGDGVTCTVPIFEGYSLPHAVSKLFVAGKDITELLTRLLLASGRAFP 205

  Fly   203 TTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSF 267
            ...::.:|.|||||||||||:.|:|::..|  ..:.:.|:||||.||.||::.::.||.||.|..
  Rat   206 CPLDKALVDDIKEKLCYVALEPEEELSRRA--EDVLREYKLPDGNVIYIGDQLYQAPEVLFSPDQ 268

  Fly   268 LGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVA 332
            ||....|:.:...|||.|||.||:|.|:...|||||:|::.|:.||:.||:..||...:.|||.|
  Rat   269 LGTHGPGLAQMASNSIAKCDADIQKTLFGEIVLSGGSTLFQGLDDRLLKELEQLASKGVPIKITA 333

  Fly   333 PPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            ||:|.:|.|||.||:.|||:|:||||:..::.|.|.|:|.|:||
  Rat   334 PPDRWFSTWIGASIVTSLSSFKQMWITAADFKEFGVSVVQRRCF 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	PTZ00281	1..376	CDD:173506	182/367 (50%)
Actrt2	NP_001013959.1	NBD_sugar-kinase_HSP70_actin	6..377	CDD:302596	182/367 (50%)
Actrt2	NP_001013959.1	ACTIN	10..377	CDD:214592	182/367 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000057
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810