DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act42A and Actr2

DIOPT Version :9

Sequence 1:	NP_523625.1	Gene:	Act42A / 35526	FlyBaseID:	FBgn0000043	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_017454617.1	Gene:	Actr2 / 289820	RGDID:	1310826	Length:	399	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	176/385 - (45%)
Similarity:	251/385 - (65%)	Gaps:	20/385 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRP------RHQGVMVGMGQK-DSYVGDEAQSKRGIL 66
            :|.|||:|..|.|:||.:.|..:||::||||      :...:.:...:| |..|||||...|.:|
  Rat     9 VVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSML 73

  Fly    67 TLKYPIEHGIVTNWDDMEKIWHHTFYNE-LRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNT 130
            .:.||:|:|||.|||||:.:|.:||..| |.:......:||||.|:||..||||:.::||||:..
  Rat    74 EVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRSCKILLTEPPMNPTKNREKIVEVMFETYQF 138

  Fly   131 PAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILT 195
            ..:||||||||:|||.|..||:|:||||||:|..|:|||::|||...|||:||||:|.||:|:|.
  Rat   139 SGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLL 203

  Fly   196 ERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPE 260
            .|||:|..:|:.|.||.||||||||..:.|||...|..::.|.:||.||||::|.:|.|||..||
  Rat   204 LRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPE 268

  Fly   261 SLFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITAL---- 321
            :||||..:.:|..|:.|..:|:|...|:|.|.:.|.:.|||||:|||||:..|:::|:..|
  Rat   269 ALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLER 333

  Fly   322 -------APSTMKIKIVAPPERKYSVWIGGSILAS-LSTFQQMWISKQEYDESGPSIVHR 373
                   ..|..||:|..||.||:.|::||::||. :......|:::|||.|.|..::.:
  Rat   334 VLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	PTZ00281	1..376	CDD:173506	176/385 (46%)
Actr2	XP_017454617.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820