Protein Alignment Act42A and ACTRT2

DIOPT Version :10

• Sequence 1: NP_523625.1
• Gene: Act42A / 35526
• FlyBaseID: FBgn0000043
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_536356.3
• Gene: ACTRT2 / 140625
• HGNCID: 24026
• Length: 377
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 177/369 - (47%)
• Similarity: 252/369 - (68%)
• Gaps: 2/369 - (0%)

  Fly     8 ALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPI 72
            |::.|||||.||||.:|:..||.:..||||..:.|.......||..:||:||..|:..|.|..|.
Human    11 AVIFDNGSGFCKAGLSGEFGPRHMVSSIVGHLKFQAPSAEANQKKYFVGEEALYKQEALQLHSPF 75

  Fly    73 EHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAI 137
            |.|::|.|||:|::|.|.|..||.|.|.:.|:|.||..|||:.|||||.::|||.|..||.|::.
Human    76 ERGLITGWDDVERLWKHLFEWELGVKPSDQPLLATEPSLNPRENREKMAEVMFENFGVPAFYLSD 140

  Fly   138 QAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT 202
            ||||:||||...||:|:||||.|:.||||:|||:||||:.:|.:||||:|:.||::|...|::|.
Human   141 QAVLALYASACVTGLVVDSGDAVTCTVPIFEGYSLPHAVTKLHVAGRDITELLMQLLLASGHTFP 205

  Fly   203 TTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSF 267
            ...::.:|.|||:|||||||:.|:|:  :.....:.:.|:||||.:|::|:...:.||:||.|..
Human   206 CQLDKGLVDDIKKKLCYVALEPEKEL--SRRPEEVLREYKLPDGNIISLGDPLHQAPEALFVPQQ 268

  Fly   268 LGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVA 332
            ||.::.|:.....:||.|||.||:|.|:...|||||||::.|:.||:.||:..||.....|||.|
Human   269 LGSQSPGLSNMVSSSITKCDTDIQKILFGEIVLSGGTTLFHGLDDRLLKELEQLASKDTPIKITA 333

  Fly   333 PPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            ||:|.:|.|||.||:.|||:|:|||::..::.|.|.|:|.|:||
Human   334 PPDRWFSTWIGASIVTSLSSFKQMWVTAADFKEFGTSVVQRRCF 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	ASKHA_NBD_actin	7..371	CDD:466823	173/362 (48%)
ACTRT2	NP_536356.3	ASKHA_NBD_actin_Arp-T1-3	10..368	CDD:466848	171/358 (48%)