DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act42A and AgaP_AGAP005110

DIOPT Version :9

Sequence 1:	NP_523625.1	Gene:	Act42A / 35526	FlyBaseID:	FBgn0000043	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_313987.1	Gene:	AgaP_AGAP005110 / 1274786	VectorBaseID:	AGAP005110	Length:	418	Species:	Anopheles gambiae

Alignment Length:	411	Identity:	150/411 - (36%)
Similarity:	214/411 - (52%)	Gaps:	45/411 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALVVDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDSYVGDEAQSKRG 64
            |.|:|.|:|..|.|||.:..|:.:.||.        ||....:.|..|:...|.|:||||....|
Mosquito     7 ACVIDVGTGYTKLGFAANKEPQFIIPSAIAIKESAKVGDQSARRVTKGVEDLDFYIGDEAFDATG 71

  Fly    65 ILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN 129
             .::|||:.||:|.:||.||:......:..||..||:|..||||.|||...|||...:|||||||
Mosquito    72 -YSVKYPVRHGLVEDWDLMERFLEQCIFKYLRAEPEDHHFLLTEPPLNTPENREYTAEIMFETFN 135

  Fly   130 TPAMYVAIQAVLSLYAS-------GRT-TGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDL 186
            .|.:|:|:||||:|.||       .|| ||||:||||||:|.:|:.|||.:...|..:.:|||::
Mosquito   136 VPGLYIAVQAVLALAASWASRPVEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRNI 200

  Fly   187 TDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMAT-AASSSSLEKSYE-------L 243
            |.::..:|.||..........|..:.|||:..|:..|..:|.|. .|..:...:.||       .
Mosquito   201 TSFIQSLLREREVGIPPEQSLETAKAIKERYSYICPDIAKEFAKYDAEPTKWMRHYEGINAITKQ 265

  Fly   244 PDGQVITIGNERFRCPESLFQPSFLGME-ACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMY 307
            |.|  :.:|.|||..||..|.|.|...: ...:.|.....|..|.:|:|:.||.|.|||||:||:
Mosquito   266 PFG--VDVGYERFLGPEIFFHPEFSNPDFTTPLSEIVDTVIQNCPIDVRRPLYNNIVLSGGSTMF 328

  Fly   308 PGIADRMQKEIT----------------ALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQM 356
            .....|:|::|.                .:.|..:.:.:::...::|:||.|||:|||...|.|:
Mosquito   329 RDFGRRLQRDIKRSVDARLRISENLSEGRIKPKPIDVSVISHHMQRYAVWFGGSMLASTPEFYQV 393

  Fly   357 WISKQEYDESGPSIV-HRKCF 376
            ..:|..|:|.||.|. |...|
Mosquito   394 CHTKAAYEEYGPGICRHNPVF 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	PTZ00281	1..376	CDD:173506	149/409 (36%)
AgaP_AGAP005110	XP_313987.1	PTZ00280	4..417	CDD:240343	150/411 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820