Protein Alignment Act42A and ACTR1A

DIOPT Version :10

• Sequence 1: NP_523625.1
• Gene: Act42A / 35526
• FlyBaseID: FBgn0000043
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005727.1
• Gene: ACTR1A / 10121
• HGNCID: 167
• Length: 376
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 197/370 - (53%)
• Similarity: 279/370 - (75%)
• Gaps: 7/370 - (1%)

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 73
            :|:|||||:.|||||||..|:..||:.||||:|..||.|..:.|.::|.:|:..||:|:::||:|
Human    12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPME 76

  Fly    74 HGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAI 137
            ||||.:|:|||:||.:.: .::|:...||||||||||||||:.|||:..::.|||||.||:::::
Human    77 HGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISM 141

  Fly   138 QAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT 202
            ||||||||:|||||:||||||||:|.||||||:|:||:|:|:|:||||::.:|...|.:.||.|.
Human   142 QAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFH 206

  Fly   203 TTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKS-YELPDGQVITIGNERFRCPESLFQPS 266
            :::|.|||:.|||:.||::::.:::     .:...||: |.||||..|.||..|||.||.||:|.
Human   207 SSSEFEIVKAIKERACYLSINPQKD-----ETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPD 266

  Fly   267 FLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIV 331
            .:|.|:.||||....:|.|.|:|:|:.|::|.|||||:|::.|..||:..|:..|||..:||:|.
Human   267 LIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRIS 331

  Fly   332 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            ||.||.||.||||||||||.||::||:||:||:|.|...:|||.|
Human   332 APQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	ASKHA_NBD_actin	7..371	CDD:466823	193/363 (53%)
ACTR1A	NP_005727.1	ASKHA_NBD_Arp1	9..375	CDD:466820	195/367 (53%)