Protein Alignment Act42A and ACTR1B

DIOPT Version :10

• Sequence 1: NP_523625.1
• Gene: Act42A / 35526
• FlyBaseID: FBgn0000043
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005726.1
• Gene: ACTR1B / 10120
• HGNCID: 168
• Length: 376
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 201/370 - (54%)
• Similarity: 277/370 - (74%)
• Gaps: 7/370 - (1%)

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 73
            :|:|||||:.|||||||..|:..||:.||||:|..||.|..:.|.::|.:|:..||:||::||:|
Human    12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPME 76

  Fly    74 HGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAI 137
            ||:|.:|:|||:||.:.: .::|:...||||||||||||||..||||..::.|||||.||:::::
Human    77 HGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISM 141

  Fly   138 QAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT 202
            ||||||||:|||||:||||||||:|.||||||:|:||:|:|:|:||||::.||..:|.:.|..|.
Human   142 QAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFH 206

  Fly   203 TTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEK-SYELPDGQVITIGNERFRCPESLFQPS 266
            |:||.|:||.|||:.||::::.:::.|.     ..|| .|.||||..:.:|..|||.||.||||.
Human   207 TSAEFEVVRTIKERACYLSINPQKDEAL-----ETEKVQYTLPDGSTLDVGPARFRAPELLFQPD 266

  Fly   267 FLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIV 331
            .:|.|:.|:||....:|.|.|:|:|:.|:||.|||||:|::.|..||:..|:..|||..:||||.
Human   267 LVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKIS 331

  Fly   332 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 376
            ||.||.||.||||||||||.||::||:||:||:|.|...:|||.|
Human   332 APQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	ASKHA_NBD_actin	7..371	CDD:466823	197/363 (54%)
ACTR1B	NP_005726.1	ASKHA_NBD_Arp1	9..375	CDD:466820	199/367 (54%)