DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Src42A and LSB1

DIOPT Version :9

Sequence 1:	NP_610191.2	Gene:	Src42A / 35524	FlyBaseID:	FBgn0264959	Length:	1597	Species:	Drosophila melanogaster
Sequence 2:	NP_011652.1	Gene:	LSB1 / 853037	SGDID:	S000003368	Length:	241	Species:	Saccharomyces cerevisiae

Alignment Length:	212	Identity:	37/212 - (17%)
Similarity:	75/212 - (35%)	Gaps:	31/212 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   816 KNDIYQKYDKYMTYGTIYEILHRKTSQSSDPWQRKSLSSILEGGRSSGDIIYDIGQRRERDKRTL 880
            :|::....:..:..|.|:|:::.|..:..|..||...::..|   ...:.:||...:::.|....
Yeast    14 RNELEFLKESNVISGDIFELINSKLPEKWDGNQRSPQNADTE---EYVEALYDFEAQQDGDLSLK 75

  Fly   881 GSSSSATVSTINPHKYGTIYDILQGVKIDAGHVKNKPDQKSKP---------------TKPPLAK 930
            .......:..|:|..|....:...|: ..|.:||....:.:.|               ..||..:
Yeast    76 TGDKIQVLEKISPDWYRGKSNNKIGI-FPANYVKPAFTRSASPKSAEAASSSTVSRPSVPPPSYE 139

  Fly   931 P--TRFVVSQVVEPVQIPPTDQSGKSVQEQGAPKSNKPNKMRRLSNILSYSRNSGEDQQETTGKE 993
            |  :::...||..|...|.........|:|.||....|          .::....:.||:.....
Yeast   140 PAASQYPSQQVSAPYAPPAGYMQAPPPQQQQAPLPYPP----------PFTNYYQQPQQQYAPPS 194

  Fly   994 ETKPKRTQAKRRIGVTN 1010
            :..|...|.::..|.::
Yeast   195 QQAPVEAQPQQSSGASS 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233
		PTKc_Frk_like	1319..1587	CDD:270653
		Pkinase_Tyr	1328..1580	CDD:285015
LSB1	NP_011652.1	SH3	55..108	CDD:214620	9/56 (16%)
LSB1	NP_011652.1	PRK14971	<100..>156	CDD:237874	11/56 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000