Protein Alignment Src42A and yes1

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_001008186.1
• Gene: yes1 / 493548
• XenbaseID: XB-GENE-495082
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 416
• Identity: 242/416 - (58%)
• Similarity: 298/416 - (71%)
• Gaps: 17/416 - (4%)

  Fly  1184 SLTTAKKG--KSRRLSEFTRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDY 1246
            |:.|.|.|  .|..::.   .:.:..:.|||.|:.|.:||:.||.|.|:.|.||:|:||:....|
 Frog   127 SIATGKTGYIPSNYVAP---ADSIQAEEWYFGKMGRKDAERLLLNPGNQRGTFLVRESETTKGAY 188

  Fly  1247 SLSVRD-----GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIE 1306
            |||:||     ||.||||:||:||.||::|..|..|.:||:||:|||:.:||||..|...|..:
 Frog   189 SLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYSEHADGLCYRLTTVCPTV- 252

  Fly  1307 KPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAE 1371
            ||.|:|||   :|.|||.|.||:...|||.|.||:||.|.||.||.|||||||.|||.|:.||.|
 Frog   253 KPQTQGLS---KDAWEIPRESLRLDVKLGQGCFGEVWIGTWNGTTKVAIKTLKPGTMMPEAFLQE 314

  Fly  1372 AQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAA 1436
            |||||||||.||:.||||.: ||||||:||.|..||||::|:  .|.|:.||:..|:|||||||.
 Frog   315 AQIMKKLRHDKLVPLYAVVS-EEPIYIVTEYMTKGSLLDFLK--EGDGKYLKLPQLVDMAAQIAD 376

  Fly  1437 GMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYS 1501
            ||||:|..|||||||.|.|:||||..:.|||||||||||:::||.||.||:|||||||||||.|.
 Frog   377 GMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG 441

  Fly  1502 KFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKD 1566
            :|:|||||||||||||||||.||:|||||.|.|||.|||.|||||.|..|...|:|:|..||.||
 Frog   442 RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKD 506

  Fly  1567 PMRRPTFETLQWKLEDFYTSDQSDYK 1592
            |..|||||.:|..|||::|:.:..|:
 Frog   507 PDERPTFEYIQSFLEDYFTATEPQYQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	50/95 (53%)
		PTKc_Frk_like	1319..1587	CDD:270653	179/267 (67%)
		Pkinase_Tyr	1328..1580	CDD:285015	169/251 (67%)
yes1	NP_001008186.1	SH3_Yes	88..145	CDD:212940	5/20 (25%)
		SH2_Src_family	148..247	CDD:199827	50/98 (51%)
		PTKc_Yes	258..536	CDD:270654	183/281 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8785
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3556
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040