Protein Alignment Src42A and lyn

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_001004543.1
• Gene: lyn / 447804
• ZFINID: ZDB-GENE-040912-7
• Length: 510
• Species: Danio rerio
• Alignment Length: 529
• Identity: 238/529 - (44%)
• Similarity: 331/529 - (62%)
• Gaps: 54/529 - (10%)

  Fly  1087 QHRCLQQHQQTPLAKKHSLDNCLQVVSSTTSRQPLRRWSNQTPLKCTCHPATEE----LPLTAIE 1147
            |:.|:.:    |:.|:|.:......|...||.:|               |.|.:    ||....:
Zfish    12 QNGCVLE----PVNKEHPVRTDQTYVRDPTSYKP---------------PITSQNAGLLPGQVFQ 57

  Fly  1148 KSRSLPAACSASCSHTCAH-----------LSVIDQSPATTKCFGKTSLTTAKKG--KSRRLSEF 1199
            |.........|...:...|           |.:|::.....|.   .||||.|:|  .|..::|
Zfish    58 KMEEKEKIVVALYPYEAIHADDLGFKKGEKLKIIEEHGEWWKA---RSLTTRKEGFIPSNYVAE- 118

  Fly  1200 TRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD-----GDTVKHY 1259
              .:.:..:.|:::.|.|.:||::||.|.|:.|::|||:||:....||||:||     .|.||||
Zfish   119 --ADTMETEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHY 181

  Fly  1260 RIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEID 1324
            :||.||.||::|:.:.||..:..:::||.|.|||||..|.|.|   |||..:  ....:|.|||.
Zfish   182 KIRSLDNGGYYISPKITFSDISSMIKHYHKQSDGLCRKLDKAC---EKPKAQ--KPWDKDAWEIS 241

  Fly  1325 RTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAV 1389
            :.|:|.|:|||:||||:||...:||:|.||:||||.|||..:.||.||.:||.|:|.:|::||||
Zfish   242 KDSIKMVKKLGAGQFGEVWMAFYNNSTKVAVKTLKPGTMSVEAFLEEANLMKTLQHDRLVRLYAV 306

  Fly  1390 CTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAAR 1454
            .|..||||||||.|.:||||::|::.||.  .:::..|||.:||||.||||:|.:|||||||.|.
Zfish   307 VTKTEPIYIITEYMANGSLLDFLKSQAGS--KIQLPKLIDFSAQIAEGMAYIEKKNYIHRDLRAA 369

  Fly  1455 NVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTEL 1519
            ||||.:..:.|||||||||:|::|:|.||.||:||||||||||.||..|:||||:||||:||.|:
Zfish   370 NVLVSEMLLCKIADFGLARVIEDDQYTAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEI 434

  Fly  1520 VTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFY 1584
            :|||:||||||:|:||::.|:.|||||:|.||...|||||..||...|..||||:.:|..|:|||
Zfish   435 ITYGKIPYPGMSNSEVMSSVQRGYRMPRPENCPVELYEIMTTCWKNKPEDRPTFDYIQSVLDDFY 499

  Fly  1585 TSDQSDYKE 1593
            |:.:..|::
Zfish   500 TATEGQYQQ 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	44/95 (46%)
		PTKc_Frk_like	1319..1587	CDD:270653	161/267 (60%)
		Pkinase_Tyr	1328..1580	CDD:285015	151/251 (60%)
lyn	NP_001004543.1	SH3_Lyn	65..120	CDD:212937	13/60 (22%)
		SH2_Src_Lyn	123..223	CDD:198227	44/99 (44%)
		PTKc_Lyn	237..508	CDD:270657	161/272 (59%)
		Pkinase_Tyr	245..495	CDD:285015	151/251 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010