Protein Alignment Src42A and Itk

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_001102295.2
• Gene: Itk / 363577
• RGDID: 1311618
• Length: 620
• Species: Rattus norvegicus
• Alignment Length: 403
• Identity: 156/403 - (38%)
• Similarity: 242/403 - (60%)
• Gaps: 27/403 - (6%)

  Fly  1199 FTRGEFLNEKS--------WYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSV----- 1250
            :....:|.|||        ||.:.|.|.:|| ||||...:.|||::|||.: ...|::||
  Rat   220 YAPSSYLVEKSPNSLETYEWYNKSISRDKAE-KLLLDTGKEGAFMVRDSRT-PGTYTVSVFTKAI 282

  Fly  1251 --RDGDTVKHYRIRQLDEG--GFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKP-CVQIEK-PV 1309
              .:...:|||.|::.::.  .:::|.:..|.::..|::::..:..||...|..| |...:| ||
  Rat   283 ISENNPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPV 347

  Fly  1310 TEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQI 1374
            |.||.:   .:|.|..:.|.||:::||||||.|..|.|.|...|||||::.|.|..:||:.||::
  Rat   348 TAGLRY---GKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEV 409

  Fly  1375 MKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMA 1439
            |.||.|.||:|||.||..:.||.::.|.|:||.|.:||::..|   ....:||:.|...:..|||
  Rat   410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRG---LFAAETLLGMCLDVCEGMA 471

  Fly  1440 YLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFS 1504
            |||....|||||||||.|||:..::|::|||:.|.:.:|:|.:..|.:||:||.:||..::|::|
  Rat   472 YLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYS 536

  Fly  1505 IKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMR 1569
            .||||||||:|:.|:.:.|:|||...:|:||:..:..|:|:.:|....|.:|::|..||.:.|..
  Rat   537 SKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASPHVYQVMNHCWKEKPED 601

  Fly  1570 RPTFETLQWKLED 1582
            ||.|..|..:|.:
  Rat   602 RPPFSRLLSQLAE 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	29/99 (29%)
		PTKc_Frk_like	1319..1587	CDD:270653	115/264 (44%)
		Pkinase_Tyr	1328..1580	CDD:285015	112/251 (45%)
Itk	NP_001102295.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910