Protein Alignment Src42A and Y50D4B.6

DIOPT Version :10

• Sequence 1: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Sequence 2: NP_503375.2
• Gene: Y50D4B.6 / 3565593
• WormBaseID: WBGene00021745
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 361
• Identity: 110/361 - (30%)
• Similarity: 174/361 - (48%)
• Gaps: 55/361 - (15%)

  Fly  1278 RTLQELVEHYSKDSDGLCVNLCKPCVQTNSFSGVFEIE-KPVTEGLSHRTRDQ-WEIDRTSLKF- 1339
            |:|:..:.|.|.......|...:..:|.|..:....:| :|:...:.:...|: :|||.....|
 Worm    40 RSLESGIIHSSSQKTPSSVRENESLLQANEENVPIGLETEPINAIIKNLKFDERFEIDVNKFSFY 104

  Fly  1340 -VRKLGSGQFGDVWE---------GL-WNNTTPVAIKTLKSGTMDPKDFLAEAQIM-KKL----- 1387
             :..||:|.:|.|::         || ..|:..||:|.    .:.|:| .:|.|:| ::|
 Worm   105 NLSFLGNGYYGKVFKERMHKKQKNGLDSENSLEVAVKR----ALRPED-PSEQQLMCEELNVMCV 164

  Fly  1388 --RHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQA-----------IAGKGRSLKMQTLIDM 1439
              :|..::.|.......| |.|::|.::.|.|:|||:|           :...||.|....|:..
 Worm   165 VGKHPNILALIRWIRTNE-ILIVSEFVEKGDLVEYLRARRRYFNKDIVCVEDNGRLLCPTDLLSF 228

  Fly  1440 AAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDE-YEARVGARFPIKWTA 1503
            |.|||.||.:|.:...:|||||.|||.|....|::||||||||..:..| |..:....||:||.|
 Worm   229 AFQIANGMKFLGNVACVHRDLALRNVFVKRNRIIRIADFGLARWHENKEYYRKKTDVGFPMKWLA 293

  Fly  1504 PEAANYS------KFSIKSDVWSFGILLTELVTYGRIPYPGMTNAE-----VLTQVEHGYRMPQP 1557
            ||...:.      ||..|||:||:|:.|.|:.:.|..||.|:....     ::..|..|.::|.|
 Worm   294 PECFEFEQERENIKFDSKSDIWSYGVCLYEIFSLGVSPYEGLDFRPDYFQGLMKYVRDGNQLPSP 358

  Fly  1558 PNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFY 1593
            .:...::||.|..||:.:|.:||.|.    :..||:
 Worm   359 EHGSDKIYEFMQSCWNLNPDKRPVFS----ECRDFF 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233	5/22 (23%)
		PTKc_Frk_like	1328..1596	CDD:270653	101/310 (33%)
Y50D4B.6	NP_503375.2	PTKc	109..391	CDD:270623	96/292 (33%)