Protein Alignment Src42A and Src

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: XP_006499126.1
• Gene: Src / 20779
• MGIID: 98397
• Length: 552
• Species: Mus musculus
• Alignment Length: 419
• Identity: 237/419 - (56%)
• Similarity: 297/419 - (70%)
• Gaps: 17/419 - (4%)

  Fly  1184 SLTTAKKG--KSRRLSEFTRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDY 1246
            ||:|.:.|  .|..::.   .:.:..:.|||.||.|.|:|:.||..||..|.||:|:||:....|
Mouse   142 SLSTGQTGYIPSNYVAP---SDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAY 203

  Fly  1247 SLSVRDGD-----TVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIE 1306
            .|||.|.|     .||||:||:||.|||:|..||.|.:||:||.:|||.:||||..|...| ...
Mouse   204 CLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVC-PTS 267

  Fly  1307 KPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAE 1371
            ||.|:||:   :|.|||.|.||:...|||.|.||:||.|.||.||.|||||||.|||.|:.||.|
Mouse   268 KPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQE 329

  Fly  1372 AQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAA 1436
            ||:||||||.||:|||||.: ||||||:||.|..||||::|:...||  .|::..|:||:||||:
Mouse   330 AQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKGETGK--YLRLPQLVDMSAQIAS 391

  Fly  1437 GMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYS 1501
            ||||:|..||:||||.|.|:|||:..:.|:|||||||||:::||.||.||:|||||||||||.|.
Mouse   392 GMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG 456

  Fly  1502 KFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKD 1566
            :|:|||||||||||||||.|.||:|||||.|.|||.|||.|||||.||.|...|:::|.:||.|:
Mouse   457 RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKE 521

  Fly  1567 PMRRPTFETLQWKLEDFYTSDQSDYKEAQ 1595
            |..|||||.||..|||::||.:..|:..:
Mouse   522 PEERPTFEYLQAFLEDYFTSTEPQYQPGE 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	51/95 (54%)
		PTKc_Frk_like	1319..1587	CDD:270653	173/267 (65%)
		Pkinase_Tyr	1328..1580	CDD:285015	163/251 (65%)
Src	XP_006499126.1	SH3_Src	87..159	CDD:212941	5/19 (26%)
		SH2_Src_Src	163..263	CDD:198228	51/99 (52%)
		PTKc_Src	276..552	CDD:270656	175/278 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I9017
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52589
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930