Protein Alignment Src42A and Y47G6A.5

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_491175.2
• Gene: Y47G6A.5 / 189992
• WormBaseID: WBGene00021635
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 193/630 - (30%)
• Similarity: 291/630 - (46%)
• Gaps: 124/630 - (19%)

  Fly  1034 EHSQEPEEKCASEEQMCTRN----ALTKSSSLDAISLSV-AISPASSPSPPRPRRSLKQHRCLQQ 1093
            :||.. |:|...:|:...|.    .|....|..:..|:: .:.|.|:||...|
 Worm     4 KHSHH-EKKNKKDERNNNREYRSAVLLDDGSFSSQELALRPVMPESTPSVAVP------------ 55

  Fly  1094 HQQTPLAKKHSLDNCLQVVSSTTSRQPL---RRWSNQTPL-------KCTCHP---ATEELPLTA 1145
                  ||...|....|.||||..|.|:   |..||..|.       ..:.||   :|:.:|..|
 Worm    56 ------AKPPPLRPSTQSVSSTDPRPPIPPRRSESNLVPPPIPHHSGNISRHPSATSTKSVPNGA 114

  Fly  1146 ------IEKSRSLPAACSASCSH-----------------TCAHLSV--------IDQSPATTKC 1179
                  :.|:.|...  ||.|||                 |...:||        |:||
 Worm   115 SFSPRPVSKTHSHHG--SAKCSHSEPEEKMLIVENRFLAQTPKEMSVEEGDVLYLIEQS------ 171

  Fly  1180 FGKTSLTTAKKGKSRRLSEF------TRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRD 1238
             .:.....|  .|||:...|      ...|:  .:.|:...|..|.||::::.|:...|:||||:
 Worm   172 -NREWWYVA--SKSRQFKGFVPKSHVVYAEY--REPWFAGNISSILAEQRVMQPQLPIGSFLIRE 231

  Fly  1239 SESRHNDYSLSVRD--GDTVKHYRI-RQLDEGGFFIARR-----TTFRTLQELVEHYSKDSDGLC 1295
            : |:.:.:.|.||.  .::.:.|.| |:.::.||.|...     ..|.:|.:||.|||.:.....
 Worm   232 N-SKTDTFVLVVRSSHNESPQAYIIYRRPNQEGFEIRDNHRPAVIHFGSLHQLVNHYSCEKVPGE 295

  Fly  1296 VNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLK- 1359
            :.:|....:...|:.|...:....:..::|:.::.|:::|.||||:|:...|.. ..||:|:||
 Worm   296 IQICTKLTKAAPPLPEQTEYMAMKKIHVNRSEVRRVKEIGRGQFGEVYLAKWKG-VDVAVKSLKP 359

  Fly  1360 --SGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSL 1422
              |..:....||.||:.:.||.|..:|.|.|||..::|..||||.|.:||||.:||.:.   ::|
 Worm   360 DHSEQLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLT---KTL 421

  Fly  1423 -----------KMQTLI--DMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGN-----IVKIADF 1469
                       :...||  .::||:|:||.||.:...:||||||||||||..:     :||:|||
 Worm   422 PPIPLMSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADF 486

  Fly  1470 GLARL--IKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTN 1532
            ||||.  :.::.|..:.....|.||.|||..:...|:.|:||||:||||.|:.|.|:.||.|...
 Worm   487 GLARKTDVGDENYVMKTDNMLPWKWMAPECFDEQIFNTKTDVWSYGILLWEIGTLGKTPYRGWDY 551

  Fly  1533 AEVLTQVEHGYRMPQPPNCEPRLYEIMLE-CWHKDPMRRPTFETL 1576
            ...|..:..||.:|:|......:||...: |.|.||.|||||:.|
 Worm   552 EGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRL 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	29/98 (30%)
		PTKc_Frk_like	1319..1587	CDD:270653	110/282 (39%)
		Pkinase_Tyr	1328..1580	CDD:285015	109/273 (40%)
Y47G6A.5	NP_491175.2	SH3	151..194	CDD:302595	11/51 (22%)
		SH2	201..305	CDD:301589	29/104 (28%)
		TyrKc	328..600	CDD:197581	109/273 (40%)
		PTKc	332..601	CDD:270623	108/269 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920