Protein Alignment Src42A and T06C10.3

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_501307.1
• Gene: T06C10.3 / 188160
• WormBaseID: WBGene00020289
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 153/609 - (25%)
• Similarity: 257/609 - (42%)
• Gaps: 126/609 - (20%)

  Fly  1015 LDSEELYTRIIAQQRGLDKEHSQEPEEKCASEEQMCTRNALTKSSSLDAI--SLSVAISPASSPS 1077
            :.|.||:||.:..|..:...:|:                :.|.|||.::|  ..:.|::.|||||
 Worm     1 MGSNELFTRSVYMQSSVYSNNSK----------------SSTSSSSSNSIPTQSAPAMNAASSPS 49

  Fly  1078 PPRPRRSLKQHRCLQQHQQTPLAKKHSLDNCLQV---------VSSTTSRQPLRRWSNQTPLKCT 1133
                :...||.:   :..:..:.:|..::..::.         |.||      :...|...||
 Worm    50 ----KEPAKQEK---EDDKKEVEEKKEIEKSVEAKVEGKVKAKVEST------QNTDNSQELK-- 99

  Fly  1134 CHPATEELPLTAIEKSRSLPAACSASCSHTCAHLSVIDQSPATTKCFGKTSLTTAKKGKSRRLSE 1198
               |.||.|....:|..:|..:.|..      .||::.:         |...:..:|    :|.|
 Worm   100 ---APEEKPKKKKKKKSNLIVSASVE------KLSIVPE---------KEDFSILEK----KLRE 142

  Fly  1199 FTRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDY----------------S 1247
            |         ::|...:.|.:....|..|    |.||:|.||....::                |
 Worm   143 F---------NFYHGFLPREDLHTTLHNP----GDFLLRVSEVVEGEHKVNREVILSLIPVSTVS 194

  Fly  1248 LSVRDGDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEG 1312
            ....|...|::..|::: ...||.....||.::.:||.:|:|:..| |.:   ...|::.|:.:
 Worm   195 KDEEDRKKVRNVVIKRV-TNLFFCEITRTFESISDLVTYYTKNPGG-CAS---GTFQLKHPILQ- 253

  Fly  1313 LSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEG---LWNNT-TPVAIKTLKSGT----MDPKDFL 1369
                  ..||...:.:...:.||.|.||.|..|   |.:.| ..||||..|...    |..|:.:
 Worm   254 ------QSWEFMHSDVTVGKVLGEGAFGKVCSGTLKLKDGTNVDVAIKMTKVSAFLSKMKIKEMM 312

  Fly  1370 AEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQI 1434
            .||:.::...|..:::||.|...|:|:||:.||:|.|||.::::...|   ::.:...|...:..
 Worm   313 NEARFIRNFNHKNVVRLYGVAHHEQPLYILLELVKGGSLQDHMKKEKG---AVSIVEKIKFCSGA 374

  Fly  1435 AAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAAN 1499
            ..|:.||...|.||||:||||.|:.:.. |||.||||:|  ....|:.:...:.|:||.|||..:
 Worm   375 GRGIEYLHQNNCIHRDIAARNCLLHEKE-VKITDFGLSR--TGPVYKMKTACKLPVKWLAPETLS 436

  Fly  1500 YSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWH 1564
            ...||..:|.:|:|:...|:...|..|:.|:.|:.|.|.:.....:..||.....:.:.|.....
 Worm   437 TLSFSFATDTYSWGVTCYEVFADGVEPFFGIQNSVVKTDILANKFLQMPPTTPESIKKYMEASIF 501

  Fly  1565 KDPMRRPT-------FETLQWKLE 1581
            .:..||.|       ||.::..||
 Worm   502 VEGSRRATMTSAIAEFEKIKSALE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	24/106 (23%)
		PTKc_Frk_like	1319..1587	CDD:270653	86/278 (31%)
		Pkinase_Tyr	1328..1580	CDD:285015	82/266 (31%)
T06C10.3	NP_501307.1	SH2_Fps_family	138..236	CDD:198224	25/115 (22%)
		TyrKc	263..517	CDD:197581	80/259 (31%)
		PTKc	267..518	CDD:270623	80/256 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920