Protein Alignment Src42A and scd-2

DIOPT Version :10

• Sequence 1: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Sequence 2: NP_504685.3
• Gene: scd-2 / 179054
• WormBaseID: WBGene00004740
• Length: 1421
• Species: Caenorhabditis elegans
• Alignment Length: 265
• Identity: 93/265 - (35%)
• Similarity: 135/265 - (50%)
• Gaps: 15/265 - (5%)

  Fly  1332 IDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIK----TLKSGTMDPKDFLAEAQIMKKLRHTKL 1392
            |.|.|::..|.||.|.||:|:.|.::. ..:|:|    |..:......||..||..|.......:
 Worm   971 ISRDSIERGRVLGRGNFGEVYYGEYSG-VKLAVKMISRTFSASQASQSDFCNEALCMGTFVDENV 1034

  Fly  1393 IQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLK-----MQTLIDMAAQIAAGMAYLES 1452
            ::|..:...:.|..|..|.|:.|.||.:::.......||.     |..||.:...:|||...||:
 Worm  1035 VRLIGIDFEKVPYMIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKICCDVAAGCKCLET 1099

  Fly  1453 QNYIHRDLAARNVLV---GDGNIVKIADFGLARLIKEDEYEARVGAR--FPIKWTAPEAANYSKF 1512
            ..|:|||:||||:|:   |...:.||||||:|:.|.......|:..|  .|||||.|||.....|
 Worm  1100 FGYVHRDIAARNILLTTRGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKWTPPEAFIDGVF 1164

  Fly  1513 SIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPM 1577
            :.|||:||||:|..|:.:.|.:|||...|.||:..:..|.|:..|.....|:|::|.:||.....
 Worm  1165 TTKSDIWSFGVLCWEVFSLGVVPYPNRRNEEVMLMLTEGARLEYPYGIPTRVYQLMRDCWKTAAA 1229

  Fly  1578 RRPTF 1582
            .||.|
 Worm  1230 DRPKF 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233
		PTKc_Frk_like	1328..1596	CDD:270653	93/265 (35%)
scd-2	NP_504685.3	LDLa	305..338	CDD:238060
		Gly_rich	599..804	CDD:403882
		Protein Kinases, catalytic domain	969..1239	CDD:473864	93/265 (35%)