Protein Alignment Src42A and Hck

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: NP_034537.2
• Gene: Hck / 15162
• MGIID: 96052
• Length: 524
• Species: Mus musculus
• Alignment Length: 419
• Identity: 227/419 - (54%)
• Similarity: 295/419 - (70%)
• Gaps: 22/419 - (5%)

  Fly  1184 SLTTAKKG--KSRRLSEFTRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDY 1246
            ||.|.|:|  .|..::   |...|..:.|:|:.|.|.:||:.||.|.|..|:|:|||||:....|
Mouse   117 SLATKKEGYIPSNYVA---RVNSLETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSY 178

  Fly  1247 SLSVRD-----GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCV--Q 1304
            ||||||     |||||||:||.||.|||:|:.|:||.:|||||.||.|..||||..|..|||  :
Mouse   179 SLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQELVLHYKKGKDGLCQKLSVPCVSPK 243

  Fly  1305 IEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFL 1369
            .:||       ..:|.|||.|.||:..:|||:||||:||...:|..|.||:||:|.|:|..:.||
Mouse   244 PQKP-------WEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFL 301

  Fly  1370 AEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQI 1434
            |||.:||.|:|.||::|:||.: :|||:|:||.|..||||::|::..|..:.|  ..|||.:|||
Mouse   302 AEANLMKSLQHDKLVKLHAVVS-QEPIFIVTEFMAKGSLLDFLKSEEGSKQPL--PKLIDFSAQI 363

  Fly  1435 AAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAAN 1499
            :.|||::|.:|||||||.|.|:||....:.|||||||||:|:::||.||.||:||||||||||.|
Mouse   364 SEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAIN 428

  Fly  1500 YSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWH 1564
            :..|:||||||||||||.|:|||||||||||:|.||:..:|||||||:|.||...||.||:.||.
Mouse   429 FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYNIMIRCWK 493

  Fly  1565 KDPMRRPTFETLQWKLEDFYTSDQSDYKE 1593
            ..|..|||||.:|..|:||||:.:|.|::
Mouse   494 NRPEERPTFEYIQSVLDDFYTATESQYQQ 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	55/95 (58%)
		PTKc_Frk_like	1319..1587	CDD:270653	157/267 (59%)
		Pkinase_Tyr	1328..1580	CDD:285015	146/251 (58%)
Hck	NP_034537.2	SH3	80..135	CDD:302595	7/20 (35%)
		SH2_Src_HCK	138..241	CDD:198226	57/102 (56%)
		PKc_like	252..522	CDD:304357	158/272 (58%)
		Pkinase_Tyr	260..509	CDD:285015	146/251 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920