Protein Alignment Src42A and Fyn

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: XP_030100741.1
• Gene: Fyn / 14360
• MGIID: 95602
• Length: 576
• Species: Mus musculus
• Alignment Length: 419
• Identity: 243/419 - (57%)
• Similarity: 309/419 - (73%)
• Gaps: 14/419 - (3%)

  Fly  1184 SLTTAKKG--KSRRLSEFTRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDY 1246
            ||||.:.|  .|..::..   :.:..:.|||.|:.|.:||::||...|..|.||||:||:....|
Mouse   163 SLTTGETGYIPSNYVAPV---DSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAY 224

  Fly  1247 SLSVRD-----GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIE 1306
            |||:||     ||.||||:||:||.||::|..|..|.|||:||:|||:.:.|||..|..||.:..
Mouse   225 SLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGM 289

  Fly  1307 KPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAE 1371
            ..:|: ||.:|:|.|||.|.||:.:::||:||||:||.|.||..|.|||||||.|||.|:.||.|
Mouse   290 PRLTD-LSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEE 353

  Fly  1372 AQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAA 1436
            |||||||:|.||:|||||.: ||||||:||.|..||||::|:  .|:||:||:..|:|||||:||
Mouse   354 AQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLK--DGEGRALKLPNLVDMAAQVAA 415

  Fly  1437 GMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYS 1501
            ||||:|..|||||||.:.|:|||:|.|.|||||||||||:::||.||.||:|||||||||||.|.
Mouse   416 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG 480

  Fly  1502 KFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKD 1566
            :|:|||||||||||||||||.||:|||||.|.|||.|||.|||||.|.:|...|:|:|:.||.||
Mouse   481 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKD 545

  Fly  1567 PMRRPTFETLQWKLEDFYTSDQSDYKEAQ 1595
            |..|||||.||..|||::|:.:..|:..:
Mouse   546 PEERPTFEYLQGFLEDYFTATEPQYQPGE 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	50/95 (53%)
		PTKc_Frk_like	1319..1587	CDD:270653	180/267 (67%)
		Pkinase_Tyr	1328..1580	CDD:285015	170/251 (68%)
Fyn	XP_030100741.1	SH3_Fyn_Yrk	124..179	CDD:212939	6/15 (40%)
		SH2_Src_Fyn_isoform_a_like	184..284	CDD:198281	50/99 (51%)
		PTKc_Fyn	300..573	CDD:270655	181/275 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I9017
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52589
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930