Protein Alignment Src42A and frk

DIOPT Version :10

• Sequence 1: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Sequence 2: XP_002938349.1
• Gene: frk / 100488362
• XenbaseID: XB-GENE-492884
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 521
• Identity: 264/521 - (50%)
• Similarity: 348/521 - (66%)
• Gaps: 36/521 - (6%)

  Fly  1107 NCLQVVSSTTSRQPLRRWSN-------QTPLKCTCHPATEELP--LTAIEKSRSLPAACSASCSH 1162
            :||..|.....::..|..||       |.|:..|.....:..|  :...|:.|:...|..:....
 Frog    10 SCLSCVLPCVFKEEKRSGSNSFNGIVIQNPVITTQLDGPQVPPRFVNQGEQQRNSYVALYSYEGR 74

  Fly  1163 TCAHLS--------VIDQSPATTKCFGKTSLTTAKKGKSRRLSEF---TRGEFLNEKSWYFRKIK 1216
            |...||        :||.:.|:   :.|..|... :||:.....|   .....:....|:|:.||
 Frog    75 TPDELSFKAGDQMLIIDTTHAS---WWKAKLLRT-RGKAEGYVPFNYVAPVSSIESMPWFFKDIK 135

  Fly  1217 RIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGFFIARRTTFRTLQ 1281
            |.|||:.|:.|.|..|:||||:|||:..:|||||.||..|||||:|:||:|||:|..::.|.::.
 Frog   136 RSEAERLLVRPGNTTGSFLIRESESQKGEYSLSVFDGIAVKHYRLRKLDDGGFYITSKSKFVSMN 200

  Fly  1282 ELVEHYSKDSDGLCVNLCKPCVQTNSFSGVFEIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSG 1346
            ||||:|.|..:|||..|.|||:.|    |:     |:...|.:.|.|.|||:|.||||::|||.|
 Frog   201 ELVEYYGKREEGLCCKLLKPCITT----GI-----PLPPDLCYHTADHWEINRNSLKFLKKLGQG 256

  Fly  1347 QFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITEL 1411
            |||:|||||||||.||||||||:|||:|:|||.|||.||.|||.|||||.||||:|||:||||||
 Frog   257 QFGEVWEGLWNNTIPVAIKTLKTGTMNPQDFLREAQFMKNLRHPKLIQLQAVCTLEEPVYIITEL 321

  Fly  1412 MKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIA 1476
            |:|||||.|||  ...|.|:.:...:|||||:|:||||||:|::|||||||||||||:..:.|:|
 Frog   322 MRHGSLLSYLQ--NDNGTSIHIPNQVDMAAQVASGMAYLETQSFIHRDLAARNVLVGENGVYKVA 384

  Fly  1477 DFGLARLIK-EDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMT 1540
            ||||||:.| ||.|||:...:.|:|||||||..|::|:||||||:||||:.|:||||::||||:|
 Frog   385 DFGLARVFKGEDVYEAKNDTKLPLKWTAPEAIRYNRFTIKSDVWAFGILIFEIVTYGKMPYPGLT 449

  Fly  1541 NAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQA 1605
            ..:.|.::|:|||:|:|.||...||:||||||:..|..|||||||||||||::.:|.|.|.||..
 Frog   450 GRQALDKLENGYRIPKPFNCPHDLYKIMLECWNAKPEERPTFETLQWKLEDYFETDPSSYLEANN 514

  Fly  1606 Y 1606
            :
 Frog   515 F 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233	49/90 (54%)
		PTKc_Frk_like	1328..1596	CDD:270653	178/268 (66%)
frk	XP_002938349.1	SH3_Src_like	65..117	CDD:212779	12/55 (22%)
		SH2	125..220	CDD:472789	49/94 (52%)
		PTKc_Frk_like	238..505	CDD:270653	178/268 (66%)