Protein Alignment Src42A and abl2

DIOPT Version :9

• Sequence 1: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Sequence 2: XP_002937405.1
• Gene: abl2 / 100487790
• XenbaseID: XB-GENE-6459814
• Length: 1100
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 228/647 - (35%)
• Similarity: 316/647 - (48%)
• Gaps: 143/647 - (22%)

  Fly   952 GKSVQEQG--APKSNKPNKMRRLSNILSYSRNSGEDQQETTGKEETKPK-------RTQAKRR-- 1005
            |:.|...|  ||.:.:|::         .:|.||           |||.       .|.::||
 Frog     2 GQQVGRVGGEAPSAQQPHR---------GARGSG-----------TKPSAHVGNIAATSSRRREA 46

  Fly  1006 IGVTNLLLPLDSEELYTRIIAQQRGLDKEHSQEPEEKCASEEQMCTRNALTKSSSLDAISLSVAI 1070
            .|.||       .|....|..|...|.:.:..:.|.:           |||     |||
 Frog    47 TGRTN-------PETGFNIFTQHEALHRPYGSDSEPQ-----------ALT-----DAI------ 82

  Fly  1071 SPASSPSPPRPRRSLKQHRCLQQHQQTPLAKKHSLDNCLQVVSSTTSRQPLRRWSNQTPLKCTCH 1135
                                                                |||::..|
 Frog    83 ----------------------------------------------------RWSSKENL----- 90

  Fly  1136 PATEELPLTAIEKSRSLPAAC---SASCSHTCAHLSVIDQSPATTKCF---GKTSLTTAKKGKSR 1194
                   |.|.|...:|..|.   .||..:|   ||:.........|:   |:.....:|.|:..
 Frog    91 -------LGATESDPNLFLALYDFVASGDNT---LSITKGEKLRVLCYNQNGEWCEVLSKNGQGW 145

  Fly  1195 RLSEF-TRGEFLNEKSWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKH 1258
            ..|.: |....|.:.|||...:.|..||  .||....:|:||:|:|||.....|:|:|....|.|
 Frog   146 VPSNYITPVNSLEKHSWYHGPVSRSAAE--YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYH 208

  Fly  1259 YRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEI 1323
            |||....:|..::...:.|.||.|||.|:|..:|||...|..|..:..||...|:| ...|:||:
 Frog   209 YRINTASDGKVYVTAESRFNTLAELVHHHSTVADGLVTILHYPAPKCNKPTVYGVS-PIHDKWEM 272

  Fly  1324 DRTSLKFVRKLGSGQFGDVWEGLWN--NTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQL 1386
            :||.:....|||.||:|:|:.|:|.  |.| ||:||||..||:.::||.||.:||:::|..|:||
 Frog   273 ERTDITMKHKLGGGQYGEVYVGVWKKYNLT-VAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQL 336

  Fly  1387 YAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDL 1451
            ..|||:|.|.||:||.|.:|:||:||:..  ....:....|:.||.||::.|.|||.:|:|||||
 Frog   337 LGVCTLEPPFYIVTEYMHYGNLLDYLREC--NREEVTAVVLLYMATQISSAMEYLERKNFIHRDL 399

  Fly  1452 AARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILL 1516
            ||||.|||:.::||:|||||:||:..|.|.|..||:|||||||||:..|:.||||||||:||:||
 Frog   400 AARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLL 464

  Fly  1517 TELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTF-ETLQ 1577
            .|:.|||..||||:..::|...:|.||||.||..|.|::||:|..||..:|..||:| ||.|
 Frog   465 WEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWNPSDRPSFSETHQ 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	35/90 (39%)
		PTKc_Frk_like	1319..1587	CDD:270653	137/262 (52%)
		Pkinase_Tyr	1328..1580	CDD:285015	132/253 (52%)
abl2	XP_002937405.1	SH3_Abl	100..153	CDD:212784	12/55 (22%)
		SH2_ABL	158..251	CDD:198189	36/94 (38%)
		PTKc_Abl	270..532	CDD:270645	136/260 (52%)
		F_actin_bind	984..1100	CDD:385063

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910