Protein Alignment Src42A and mst1ra

DIOPT Version :10

• Sequence 1: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Sequence 2: XP_005166175.1
• Gene: mst1ra / 100002448
• ZFINID: ZDB-GENE-071218-2
• Length: 1356
• Species: Danio rerio
• Alignment Length: 408
• Identity: 125/408 - (30%)
• Similarity: 197/408 - (48%)
• Gaps: 49/408 - (12%)

  Fly  1213 RKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGF----FIAR 1273
            :|.|....|.:|.:..|...|          .:|..| .|||    ||...:...|.    |...
Zfish   954 KKKKAALVEVRLSMHSNRTTA----------ENYDRS-PDGD----YRRETVRPAGLSVSPFHGS 1003

  Fly  1274 RTTFRTLQELVEHYSKDSDGLCVNLCKPCVQTNSF-SGVFEIEKPVTEGLSHRTRDQWEIDRTSL 1337
            .|||.:|.     |:...|.....|.:..|..::. ..:.|..|.|.  :|.        |:..:
Zfish  1004 GTTFTSLP-----YAGSMDSAAAPLMRRQVSMSALRPDLLEEVKNVL--ISP--------DKIKI 1053

  Fly  1338 KFVRKLGSGQFGDVWEGLW----NNTTPVAIKTLKSGT--MDPKDFLAEAQIMKKLRHTKLIQLY 1396
            :..:.:|.|.||.|:.|..    |..|..|:|:|...|  .:.:.||.|...||...|:.::.|.
Zfish  1054 QHEQIIGKGHFGTVYHGYLTDSDNKETHCAVKSLNRITDLEEVEQFLREGLFMKAFHHSHVLSLL 1118

  Fly  1397 AVCTVEEPI-YIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDL 1460
            .:....:.: .:|...||||.|..::::   ..||..::.||....|:|.||.||.::.::||||
Zfish  1119 GIVLPSDGLPLVILPYMKHGDLRHFIRS---PERSPTVKDLIGFGLQVAKGMEYLANKKFVHRDL 1180

  Fly  1461 AARNVLVGDGNIVKIADFGLARLIKEDEY---EARVGARFPIKWTAPEAANYSKFSIKSDVWSFG 1522
            ||||.::.:...||:||||:||.:.:.||   :....|:.|:||.|.|:....||:.||||||:|
Zfish  1181 AARNCMLDESFTVKVADFGMARDVYDKEYYSIQDSKKAKLPVKWMALESLQTQKFTTKSDVWSYG 1245

  Fly  1523 ILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQW 1587
            :|:.||:|.|..|||.:...::...:..|.|:|||..|...|:.::::|||.:|.:||.|.||..
Zfish  1246 VLMWELLTRGASPYPDVDPYDITPYLMQGRRLPQPQYCFDSLWSVLMQCWHPEPEKRPGFTTLVQ 1310

  Fly  1588 KLEDFYTS-DQSDYKEAQ 1604
            .::|.::| |...|...|
Zfish  1311 AVQDIHSSLDGEHYINLQ 1328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233	22/91 (24%)
		PTKc_Frk_like	1328..1596	CDD:270653	95/278 (34%)
mst1ra	XP_005166175.1	Sema_MET_like	41..504	CDD:200509
		PSI	507..549	CDD:396154
		IPT	550..654	CDD:472823
		IPT_plexin_repeat2	655..740	CDD:238584
		IPT	742..828	CDD:214657
		PTKc_Met_Ron	1057..1318	CDD:270649	93/263 (35%)