Protein Alignment mle and AT1G26370

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_173961.3
• Gene: AT1G26370 / 839179
• AraportID: AT1G26370
• Length: 717
• Species: Arabidopsis thaliana
• Alignment Length: 780
• Identity: 213/780 - (27%)
• Similarity: 326/780 - (41%)
• Gaps: 190/780 - (24%)

  Fly   375 RQFLEFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVT 439
            ::..|.|..||||::...::..:..|.::||.|.||.|||||:.|::.:...|. :|  ..|.:|
plant    32 QKIAEHRRSLPIASVEKRLVEEVQKNDILIIVGETGSGKTTQLPQFLYNAGFCR-EG--KMIGIT 93

  Fly   440 QPRRISAISVAERVARERCE-QLGDTVGYSVRFESVFPRPYGA--ILFCTVGVLLRK--LEAGLR 499
            |||||:|::||:||| |.|| |||..||||:||:..   ..|:  :.:.|.|:|||:  |:..|.
plant    94 QPRRIAAVTVAKRVA-EECEVQLGQKVGYSIRFDDT---TSGSTRLKYMTDGLLLREALLDPHLS 154

  Fly   500 GVSHIIVDEIHERDVNSDFLLVILRDMVDT----------------------------------- 529
            ..|.|||||.|:|.|::|.||.:|:.:..|
plant   155 RYSVIIVDEAHDRSVHTDVLLALLKKIQRTRSQPVSEKTEFGNVASQVQTTTRDANGPQQNGVLK 219

  Fly   530 ------YPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRR 588
                  ...|.:|:|||::|...||:|||....:.|.||.|||
plant   220 GYQGRKLSPLKLIIMSASLDARVFSEYFGGAKAVHVQGRQFPV---------------------- 262

  Fly   589 KRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIP 653
                               :|.|....|..|...|               |:....:|.:.|  |
plant   263 -------------------DILYTVHPESDYVDAT---------------LVTIFQIHFEEK--P 291

  Fly   654 GAILVFLPGWNLIFALMKFLQN--TNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILS 716
            |.|||||.|.:.|.::.:.:|.  .||..|..:...|...|.:|.::|.|||.|.|.|..|:||:
plant   292 GDILVFLTGQDEIESVERLVQERLQNIPEDKRKLLPLAIFSALPSEQQMKVFAPAPTGFRKVILA 356

  Fly   717 TNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLC 781
            ||||||||||..|.:|||....:.:.:.....:.|...|.|||....||.|||||..||..|.|.
plant   357 TNIAETSITIPGIRYVIDPGFVKARSYDPSKGMESLDVVPASKAQTLQRSGRAGREGPGKSFRLY 421

  Fly   782 SRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCL 846
            ....|:.|||:..||:.|..|..:.|.:|.|.:..|..|  ..::.|...|:|:|...|..:..|
plant   422 PEREFEKLEDSTKPEIKRCNLSNIILQLKALGIDDIVGF--DFIDKPSRGAIIKALAELHSLGAL 484

  Fly   847 DANDEL-TPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAI---MASYSSTFSEVFSLDIGQRRL 907
            ..:.:| .|:|..::|||:||...|.::|...|.|.:.|.|   :.|..|.|.:........|..
plant   485 ADDGKLENPVGYQMSRLPLEPVYSKALILANQFNCLEEMLITVAVLSVESIFYDPREKREEARTS 549

  Fly   908 ANHQKALSGTKCSDHVAMI----VASQMWRREKQRG-----EHMEARFCDWKGLQMSTMNVIWDA 963
            .||..::.|    ||:..:    .:.:...:.|..|     :.:..::|....:...::....|.
plant   550 KNHFASVEG----DHLTYLSVYRESDEFLEKRKAAGSGNNIDKIMKKWCKENYVNSRSLKHARDI 610

  Fly   964 KQQLLDLLQQAGFP-----------EECMIS----HEVDERIDGDDPVLDVSLALLCLGLYPNIC 1013
            .:|:.:.::|.||.           ..|:.:    .....::||....|:
plant   611 YRQIREHVEQIGFNVSSCGNDMLAFRRCLAASFFLKAAQRQLDGTYRALE--------------- 660

  Fly  1014 VHKEKRKVLTTESKAALLHKTSV------NCSNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPL 1072
                       ..:...:|.|||      .|           .:|.|.::|.....|.|:::..|
plant   661 -----------SGEVVHIHPTSVLFRAKPEC-----------VIFNELMQTSKKYIKNLTIIDSL 703

  Fly  1073  1072
            plant   704  703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684
		DEXHc_DHX9	326..559	CDD:350730	78/229 (34%)
		HrpA	378..>889	CDD:441249	181/562 (32%)
		OB_NTP_bind	1002..1079	CDD:400182	11/77 (14%)
AT1G26370	NP_173961.3	HrpA	40..>715	CDD:441249	211/772 (27%)