Protein Alignment mle and AT5G10370

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_196599.2
• Gene: AT5G10370 / 830901
• AraportID: AT5G10370
• Length: 1775
• Species: Arabidopsis thaliana
• Alignment Length: 1154
• Identity: 256/1154 - (22%)
• Similarity: 447/1154 - (38%)
• Gaps: 324/1154 - (28%)

  Fly   132 DGGNRYSVIDRIQEQRDMNEAEAFDVNAAIHG-------NWTIENAKERLNIYKQTN---NIRDD 186
            |||.  |..||.|:....:....::..:|...       .|..::::     |..:|   |.|.|
plant     9 DGGR--SATDRRQQSSHSSSTNRYNSRSAQSSPPLNHRPTWNQQHSQ-----YPNSNFPPNYRRD 66

  Fly   187 YK----YTPVGPEHARSFLAELSIYVPALNRTVTARESGSNKKSASKSCAL--SLVRQLFHLNVI 245
            ..    |:|.......:|:.:| ::..|.|.  ..:...|.||...:|.||  .:..:..|:...
plant    67 RNPSSGYSPPVTRARPNFIVQL-LHPAAANS--DTKLCFSTKKQEIESLALLCEIPEESIHVPQF 128

  Fly   246 EPFSGTLKKKK------------DEQLK---PYPVKLSPNLI-----NKIDEVIKGLDLPVV--- 287
            ...:|:...::            |.:|:   .:..:|.||:|     |::.:.::.|....:
plant   129 GCIAGSFSFRQWVDARSAVVALWDYRLQGKHEFVPELIPNVIVPSDMNELKDRLRDLFSSHILSL 193

  Fly   288 -----NPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKRQESSVIPWAPPQANWNTWHACNIDEGE 347
                 ..:.:::|::.....::...|:.....:..||::....                   |.:
plant   194 MENGEGVKKVRLEIEEKSRQVVSFSSKRGLKFEVFEKKKAIEA-------------------ERD 239

  Fly   348 LATTSIDD------------LSMD-YERSLRDRRQND-------NEY----------RQFLEFRE 382
            |....:::            :..| ||..|.|..:.|       ..|          |:.....:
plant   240 LVVNRLEEFNNAMKSILRYLIGQDGYEFDLDDEEEGDVAVFCLEGAYDWRRIHCLIRRECRRLED 304

  Fly   383 KLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAI 447
            .|||.|.|.:||..|:...::::.|.||.||:||:.|::.|    ||.....:|..||||:|:|:
plant   305 GLPIYAYRRQILKKIHREQIMVLIGETGSGKSTQLVQFLAD----SGVAASESIVCTQPRKIAAM 365

  Fly   448 SVAERVARER--CEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRKL--EAGLRGVSHIIVDE 508
            ::|:||..|.  |.: .:||..:..|.|. ......:::.|...||:..  :..|.|:|.:|:||
plant   366 TLADRVREESSGCYE-ENTVSCTPTFSST-EEISSKVVYMTDNCLLQHYMKDRSLSGISCVIIDE 428

  Fly   509 IHERDVNSDFLLVILRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLED 573
            .|||.:|:|.||.:|:.::....||.:::||||.|..:.|:||..|.:|.|.||.|||
plant   429 AHERSLNTDLLLALLKKLLSRRIDLRLVIMSATADAKQLSQYFFSCGILLVNGRNFPV------- 486

  Fly   574 IIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFE 638
                                              ||.|:.      |....|::.....|.|...
plant   487 ----------------------------------EIVYSP------SDTEENSVVGGIASYVGDV 511

  Fly   639 LLEALLMHIKSKNIPGAILVFLPG-----WNLIFALMKFLQNTNIFGDTSQYQILPCHSQIPRDE 698
            :..|:.:|...|.  |.||.||..     |    |..:|:..:.|        .||.|.::..:|
plant   512 VKMAVEIHKTEKE--GTILAFLTSQAEVEW----ACERFITPSAI--------ALPLHGKLSFEE 562

  Fly   699 QRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLE 763
            |.:||:..| |..|:|.:|||||||:||..:.:|||....:...:.....::.......|:::..
plant   563 QFRVFQNHP-GRRKVIFATNIAETSLTIPGVKYVIDSGMVKESKYEPRTGMSILKVCRVSQSSAR 626

  Fly   764 QRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPP 828
            ||.|||||..||.|:.|.|:..|.::..|..||:.|..|....|.:..|.:.:|..|  ..::.|
plant   627 QRAGRAGRTEPGRCYRLYSKNDFDSMNLNQEPEIRRVHLGVALLRMLALGVNNIAEF--NFVDAP 689

  Fly   829 PVDAVIEA-EVLLREMRCLDAN--DELTPLGRLLARLPIEPRLGKMMVLGAVFGC---------A 881
            ..:|:..| :.|::....::.|  .|||..|..|.:|.:||:|||:     :.||         .
plant   690 VPEAIAMAVQNLVQLGAVVEKNGVHELTQEGHCLVKLGLEPKLGKL-----ILGCFRHRMGKEGI 749

  Fly   882 DLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARF 946
            .|.|:||:.||.|..|.:.|                                 :|.:.:.::.:|
plant   750 VLAAVMANASSIFCRVGNFD---------------------------------DKMKADRLKVQF 781

  Fly   947 CDWKGLQMSTMNVI--WDAKQQLLDLLQQAGFPEECMISHEVDERIDG------DDPVLDVSLAL 1003
            |:..|...:.::|.  |            |..|.|.......:..::.      :|.|.::
plant   782 CNQNGDLFTLLSVYKEW------------ASLPRERRNKWCWENSLNAKSMRRCEDTVKEL---- 830

  Fly  1004 LCLGLYPNICVHKEKRKVLTTESKAALL-----------HKTSVNCSNLA--VTFPYPFFVFGEK 1055
                   .||:.:|    ||..|.:..:           |...|..::||  |.....:...|.:
plant   831 -------EICIERE----LTLVSPSYWVWNPNEGTKHDKHLKMVILASLAENVAMYTGYNQLGYE 884

  Fly  1056 IRTRAVSCKQLSMVSPLQVILFGSRKIDLAANNIVRVDNWLNFDIEPELAAKIGALKPALEDLI- 1119
            :   |::.:|:.:.....::.||.:            .:|:.|          |.|...::..:
plant   885 V---ALTGQQVQLHPSCSLLAFGQK------------PSWVVF----------GELLSIVDQYLV 924

  Fly  1120 -TVACD----------NPSDILRLEEPYAQLVKVV-------KDLCVKS 1150
             ..|||          .|.|:.:::|...::.|||       |..|.||
plant   925 CVTACDFEALYMLDPPPPFDVSQMDERRLRIKKVVGCSSTVLKRFCGKS 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684	17/82 (21%)
		DEXHc_DHX9	326..559	CDD:350730	74/266 (28%)
		HrpA	378..>889	CDD:441249	156/531 (29%)
		OB_NTP_bind	1002..1079	CDD:400182	15/89 (17%)
AT5G10370	NP_196599.2	HrpA	304..>756	CDD:441249	155/526 (29%)
		OB_NTP_bind	860..937	CDD:400182	16/101 (16%)
		RING_Ubox	1561..>1591	CDD:473075
		BRcat_RBR	1646..1699	CDD:438996
		Rcat_RBR_DEAH12-like	1718..1768	CDD:439036