Protein Alignment mle and AT4G18465

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_567558.2
• Gene: AT4G18465 / 827579
• AraportID: AT4G18465
• Length: 695
• Species: Arabidopsis thaliana
• Alignment Length: 700
• Identity: 198/700 - (28%)
• Similarity: 323/700 - (46%)
• Gaps: 129/700 - (18%)

  Fly   374 YRQFLEFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYAN--- 435
            |....:.|::||:...|:|||..:.::...||.|.||.||||||.||:       .:.|:|.
plant    38 YANIEKQRQRLPVYKYRTEILYLVENHATTIIVGETGSGKTTQIPQYL-------KEAGWAEGGR 95

  Fly   436 -IYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRKL--EAG 497
             |..|||||::..:|:.|||.|....||:.|||::|||........::.|.|.|||:|::  :..
plant    96 VIACTQPRRLAVQAVSARVAEEMGVNLGEEVGYTIRFEDHTTSGVTSVKFLTDGVLIREMMEDPL 160

  Fly   498 LRGVSHIIVDEIHERDVNSDFLLVILRDMVDTYPDLHVILMSATIDTTKFSKYF----------G 552
            |...|.|::||.|||.:::|.||.:|:.:....|:|.:|:.||||:....|.:|          |
plant   161 LTKYSVIMIDEAHERSISTDILLGLLKKIQRRRPELRLIISSATIEAKTMSNFFNSSKKRHAPEG 225

  Fly   553 ICP-------VLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEIN 610
            ..|       :|.|.||.|.|:..::|:  .::|::.|..|
plant   226 STPGPKLEPAILSVEGRGFSVKIHYVEE--PVSDYIRSVVS------------------------ 264

  Fly   611 YNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFLPGWNLIFALMKFLQ- 674
                                            .::.|..:..||.:||||.|...|...:|.|:
plant   265 --------------------------------TILLINEREPPGDVLVFLTGQEDIETAIKLLEE 297

  Fly   675 --NTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICK 737
              ::| ..::|....||.:|.:.|.||..:|.|.|.|..|:||||||||||:|::.:|:|||...
plant   298 EAHSN-QKNSSGLLPLPLYSGLSRSEQELIFTPTPRGKRKVILSTNIAETSLTLEGVVYVIDSGF 361

  Fly   738 ARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARF-QALEDNLTPEMFRTP 801
            ::.|.:...:::.|......||.:..||.|||||||||.|:.|.:...| ..:.....|||.|:.
plant   362 SKQKFYNPISDIESLVVAPISKASARQRSGRAGRVRPGKCYRLYTEDYFLNQMPGEGIPEMQRSN 426

  Fly   802 LHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCLDANDELT-PLGRLLARLPIE 865
            |....:.:|.|.:.:|..|...|  ||..:|:|.|..:|..::.||.:.:|| |.|..:|.||::
plant   427 LVSTVIQLKALGIDNILGFDWPA--PPSSEAMIRALEVLYSLQILDDDAKLTSPTGFQVAELPLD 489

  Fly   866 PRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSDHVAMIVASQ 930
            |.:.||::..:..||:..:..:|:..|..| |:.:..|.::..:..|........|||..:...:
plant   490 PMISKMILASSELGCSHEIITIAAVLSVQS-VWIIARGVQKEQDEAKLRFAAAEGDHVTFLNVYK 553

  Fly   931 MWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFP-EECMISHEVDERIDGDD 994
            .:...|:     ..::|....|...:|..:.:.:.||..:.::.|.. :.|          |||
plant   554 GFLESKK-----PTQWCYKNFLNYQSMKKVVEIRDQLKRIARRLGITLKSC----------DGD- 602

  Fly   995 PVLDVSLALLCLGLYPNIC--------VHKEKRKVLTTESKAALLHKTSV 1036
              ::.....:..|.:.|.|        |:|..|     .|:...:|.:||
plant   603 --MEAVRKAVTAGFFANACRLEPHSNGVYKTIR-----GSEEVYIHPSSV 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684
		DEXHc_DHX9	326..559	CDD:350730	72/207 (35%)
		HrpA	378..>889	CDD:441249	167/538 (31%)
		OB_NTP_bind	1002..1079	CDD:400182	9/42 (21%)
AT4G18465	NP_567558.2	HrpA	48..>684	CDD:441249	195/689 (28%)