Protein Alignment mle and AT4G16680

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_001329688.1
• Gene: AT4G16680 / 827370
• AraportID: AT4G16680
• Length: 796
• Species: Arabidopsis thaliana
• Alignment Length: 710
• Identity: 216/710 - (30%)
• Similarity: 330/710 - (46%)
• Gaps: 115/710 - (16%)

  Fly   379 EFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGY---ANIYVTQ 440
            |.||.|||...|.|:|..|.:|.|::|.|.||.||||||.||:       .:.||   ..|..||
plant   130 EGREFLPIHGYREELLKLIEENQVLVIVGETGSGKTTQIPQYL-------QEAGYTKRGKIGCTQ 187

  Fly   441 PRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRKL--EAGLRGVSH 503
            |||::|:|||.|||:|...:||..||||:|||...... ..|.:.|.|:|||:|  |..|...|.
plant   188 PRRVAAMSVASRVAQEVGVKLGHEVGYSIRFEDCTSEK-TVIKYMTDGMLLRELLIEPKLDSYSV 251

  Fly   504 IIVDEIHERDVNSDFLLVILRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQ 568
            ||:||.|||.:::|.|..:::|:....|||.:|:.|||::..|||:||....:..:|||.:||::
plant   252 IIIDEAHERTLSTDILFALVKDVAKVRPDLRLIISSATLEAKKFSEYFDSARIYLIPGRRYPVEK 316

  Fly   569 FFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSES 633
            .|                                         .|..|..|.:.....:..:.::
plant   317 LF-----------------------------------------RKCPEPDYLETVIRTVVQIHQT 340

  Fly   634 DVSFELLEALLMHIKSKNIPGAILVFLPGWNLIFALMKFLQNTNIFGDT--SQYQILPCHSQIPR 696
                   ||:          |.|||||.|...|..:...|:...:...|  |:..|.|.:|.:|.
plant   341 -------EAI----------GDILVFLTGQEEIETVETNLKRRMMDLGTKGSEIIICPIYSNLPT 388

  Fly   697 DEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTN 761
            ..|.|||||.|:|..|::|:|||||||:|||.:.:|||....::..:.....:.|......||.:
plant   389 PLQAKVFEPAPKGTRKVVLATNIAETSLTIDGVKYVIDPGYCKINSYNPRTGMESLLVTPISKAS 453

  Fly   762 LEQRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALE 826
            ..||.||:||..||.||.|.:   .:.||....||:.|..|..:.||:|.|.:..:.:|  ..::
plant   454 AAQRAGRSGRTGPGKCFRLYN---IKDLEPTTIPEIQRANLASVVLTLKSLGIQDVFNF--DFMD 513

  Fly   827 PPPVDAVIEAEVLLREMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYS 891
            |||.:|:::|..||..:..||...|:|.:|..:...|::|.|.||:|....:.|:..:..:|:..
plant   514 PPPENALLKALELLYALGALDEIGEITKVGERMVEFPVDPMLSKMIVGSEKYKCSKEIITIAAML 578

  Fly   892 STFSEVFSLDIGQRRLANHQKA--LSGTK-CSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQ 953
            |..:.||.....|:..|:..:.  ...|: ..||:|::.....|:.     |:...::|..|.:|
plant   579 SVGNSVFYRPKNQQVFADKARMDFYEDTENVGDHIALLRVYNSWKE-----ENYSTQWCCEKFIQ 638

  Fly   954 MSTMNVIWDAKQQLLDLLQQAGFPEECMISHEVDERIDGDDPVLDVSLALLCLGLYPNICVHKEK 1018
            ..:|....|.:.|||.||.:.|          |:...:.:|  ||.....:..|.:|    |..|
plant   639 SKSMKRARDIRDQLLGLLNKIG----------VELTSNPND--LDAIKKAILAGFFP----HSAK 687

  Fly  1019 -------RKVLTTESKAALLHKTSVNCSNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSP 1071
                   |:|  .|.:...:|..    |.|....|..:.|:.|.:.|.....:..:.:.|
plant   688 LQKNGSYRRV--KEPQTVYVHPN----SGLFGASPSKWLVYHELVLTTKEYMRHTTEMKP 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684
		DEXHc_DHX9	326..559	CDD:350730	81/184 (44%)
		HrpA	378..>889	CDD:441249	174/516 (34%)
		OB_NTP_bind	1002..1079	CDD:400182	15/77 (19%)
AT4G16680	NP_001329688.1	HrpA	135..>750	CDD:441249	213/705 (30%)