Protein Alignment mle and AT3G26560

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_189288.1
• Gene: AT3G26560 / 822264
• AraportID: AT3G26560
• Length: 1168
• Species: Arabidopsis thaliana
• Alignment Length: 1035
• Identity: 259/1035 - (25%)
• Similarity: 425/1035 - (41%)
• Gaps: 202/1035 - (19%)

  Fly    23 RQTGPKNRQRFLCEVRVEPNTYIGVGNSTNKKDAEKNACRDFVNYLVRVGKLNTNDVPADAGASG 87
            |:...:||.|...|             |...:|.::|..||......|..:.|..|   :.|...
plant   122 RREEDRNRDRDRRE-------------SGRDRDRDRNRDRDDRRDRHRDRERNRGD---EEGEDR 170

  Fly    88 GGPRTGLEGAGMAGGSGQQKRVFDGQSGPQDLGEAYRPLNHDGGDGGNR---YSVI-DRIQEQRD 148
            ...|...|.....||.|:.:|        :|.......:..|.| |.|.   |.|. .|:....|
plant   171 RSDRRHRERGRGDGGEGEDRR--------RDRRAKDEYVEEDKG-GANEPELYQVYKGRVTRVMD 226

  Fly   149 MNEAEAFD--------VNAAIHGNWTIENAKE----RLNIYKQTNNIRDDYKYT----PVGPEHA 197
            ......||        |:.:......::.|||    .:.:|.:..:|..| ||:    .|.....
plant   227 AGCFVQFDKFRGKEGLVHVSQMATRRVDKAKEFVKRDMEVYVKVISISSD-KYSLSMRDVDQNTG 290

  Fly   198 RSFLAELSIYVPALNRTVTARESGSNKKSASK-----SCALSLVRQLFHLNVIEPFSGTLKKKKD 257
            |..       :|....:.....|.||....:|     ...:|.:| :...|.:.|....|||...
plant   291 RDL-------IPLRKPSDEDDSSRSNPSYRTKDGQVTKTGISGIR-IVEENDVAPSRRPLKKMSS 347

  Fly   258 EQLKPYPVKLSPNLINKID-----------------------EVIKGLDLPVVNPRNIKIELDGP 299
            .: :....:|..:.:.::|                       |:....|.|.......:..:|..
plant   348 PE-RWEAKQLIASGVLRVDEFPMYDEDGDGMLYQEEGAEEELEIEMNEDEPAFLQGQTRYSVDMS 411

  Fly   300 PIPLIVN----LSR-------IDSSQQDGEKRQESSVI---------PWAPPQANWNTWHACNID 344
            |:.:..|    |||       :...:::..::|:.:::         ||..|.......|...
plant   412 PVKIFKNPEGSLSRAAALQSALTKERREMREQQQRTMLDSIPKDLNRPWEDPMPETGERHLAQ-- 474

  Fly   345 EGELATTSIDDLSM-DYERSLRDRRQNDNEYRQ--FLEFREKLPIAAMRSEILTAINDNPVVIIR 406
              ||....:....| ::::....:.....:..:  ..|.||.|||..::.|::.|::||.|:::.
plant   475 --ELRGVGLSAYDMPEWKKDAFGKTPTFGQRSKLSIQEQRESLPIYKLKKELIQAVHDNQVLVVI 537

  Fly   407 GNTGCGKTTQIAQYILDDYICSGQGGY---ANIYVTQPRRISAISVAERVARERCEQLGDTVGYS 468
            |.||.|||||:.||:       .:.||   ..|..|||||::|:|||:|||.|...:||:.|||:
plant   538 GETGSGKTTQVTQYL-------AEAGYTTKGKIGCTQPRRVAAMSVAKRVAEEFGCRLGEEVGYA 595

  Fly   469 VRFESVFPRPYGAILFCTVGVLLRK--LEAGLRGVSHIIVDEIHERDVNSDFLLVILRDMVDTYP 531
            :|||.. ..|...|.:.|.|:|||:  ::..|...|.|::||.|||.:::|.|..:|:.::....
plant   596 IRFEDC-TGPDTVIKYMTDGMLLREILIDENLSQYSVIMLDEAHERTIHTDVLFGLLKKLMKRRL 659

  Fly   532 DLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDE 596
            ||.:|:.|||:|..|||.||..|.:..:|||.|||
plant   660 DLRLIVTSATLDAEKFSGYFFNCNIFTIPGRTFPV------------------------------ 694

  Fly   597 EQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFLP 661
                       ||.|.|..|..|               :...|:..|.:|:....  |.|||||.
plant   695 -----------EILYTKQPETDY---------------LDAALITVLQIHLTEPE--GDILVFLT 731

  Fly   662 GWNLI-------FALMKFLQNTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNI 719
            |...|       :..||.|..     :..:..|||.:|.:|.:.|.::|:|.|.|..|::::|||
plant   732 GQEEIDSACQSLYERMKGLGK-----NVPELIILPVYSALPSEMQSRIFDPPPPGKRKVVVATNI 791

  Fly   720 AETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRA 784
            ||.|:|||.|.:|:|...|:..::.....|.|......|:.:.:||.|||||..||.|:.|.:.:
plant   792 AEASLTIDGIYYVVDPGFAKQNVYNPKQGLESLVITPISQASAKQRAGRAGRTGPGKCYRLYTES 856

  Fly   785 RFQ-ALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCLDA 848
            .:: .:.....||:.|..|....||:|.:.:..:..|  ..::||...|:|.|...|..:..||.
plant   857 AYRNEMPPTSIPEIQRINLGMTTLTMKAMGINDLLSF--DFMDPPQPQALISAMEQLYSLGALDE 919

  Fly   849 NDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKA 913
            ...||.|||.:|..|:||.|.||::.....||:|.:..|.:...| ..:|.....::..|:.::|
plant   920 EGLLTKLGRKMAEFPLEPPLSKMLLASVDLGCSDEILTMIAMIQT-GNIFYRPREKQAQADQKRA 983

  Fly   914 LSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQ 973
            .......||:.::...:.|:.:...|.     :|....:|..::....|.::|||.::.:
plant   984 KFFQPEGDHLTLLAVYEAWKAKNFSGP-----WCFENFIQSRSLRRAQDVRKQLLSIMDK 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683	10/46 (22%)
		DSRM_DHX9_rpt2	167..241	CDD:380684	17/86 (20%)
		DEXHc_DHX9	326..559	CDD:350730	83/249 (33%)
		HrpA	378..>889	CDD:441249	172/523 (33%)
		OB_NTP_bind	1002..1079	CDD:400182
AT3G26560	NP_189288.1	GH2-like_DHX8	9..76	CDD:409668
		S1_DHX8_helicase	214..290	CDD:240189	16/76 (21%)
		HrpA	513..>1137	CDD:441249	184/605 (30%)