Protein Alignment mle and AT2G47680

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_182290.1
• Gene: AT2G47680 / 819381
• AraportID: AT2G47680
• Length: 1015
• Species: Arabidopsis thaliana
• Alignment Length: 637
• Identity: 178/637 - (27%)
• Similarity: 276/637 - (43%)
• Gaps: 121/637 - (18%)

  Fly   384 LPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAIS 448
            |||.||:..|:..|.:|.|.:|.|..||||::|:.|::|       :...|.|..|||||.:.::
plant    26 LPIMAMKRRIIDKILENRVTLIVGEPGCGKSSQVPQFLL-------EANMAPILCTQPRRFAVVA 83

  Fly   449 VAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCTVGVLL-RKLEAGLRGVSH--IIVDEIH 510
            ||:.||:.|...||..:||.:....:.... ..|||.|.|||| ..|:.||..:.:  ||:||:|
plant    84 VAKMVAKSRNSDLGGEIGYHIGHSKILTEG-SKILFKTAGVLLDEMLDKGLNALKYKVIILDEVH 147

  Fly   511 ERDVNSDFLLVILRDMVDTYPDLHVILMSATIDTTKFSKYF---GICPVLEVPGRAFPVQQ---- 568
            ||.|.||.:||.::..:....||.|:|||||.|.|::..||   |....:||.....|.|:
plant   148 ERSVESDLVLVCVKQFLMKNNDLRVVLMSATADITRYRDYFKELGRGERVEVVAIPSPDQRTIFQ 212

  Fly   569 ---FFLEDII-------QMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKT 623
               .:||.:.       .::.:.|.........|::.|.|.|..|.
plant   213 RRVLYLEQVAGLLGVSSDLSAYCPGPSPSSADTEIKPELQNLIHDL------------------- 258

  Fly   624 RNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQIL 688
                              .|.:|.|..:|..:||||||.:   ::|.:.......|..:.:..||
plant   259 ------------------ILYIHEKEPDIEKSILVFLPTY---YSLEQQYHQLEPFFASFEVHIL 302

  Fly   689 PCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYA 753
              |..|. .||......:.....|:||:|||||:|:||..:.:|||.|::....:.......:..
plant   303 --HRSID-TEQALAAMKICRSRRKVILATNIAESSVTIPKVAYVIDSCRSLQVFWDPSRKRDAVQ 364

  Fly   754 TVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTI---KLLRLG 815
            .||.|::..|||:||.||...|..:.|...|.|..||::..|.:.:..|.:..|.|   :...:.
plant   365 LVWVSRSQAEQRRGRTGRTCDGEVYRLVPSAFFNKLEEHEPPSILKLSLRQQVLHICCTESRAIN 429

  Fly   816 SIHHFLSKALEPPPVDAVIEAEVLLREMRCLDAND----ELTPLGRLLARLPIE-------PRLG 869
            ..:..|:||::||..|.|.:|..:|..::.|..:.    |.|..|||||..|:.       .:.|
plant   430 DANALLAKAMDPPDPDVVDDALRMLLSIQALRKSPRGRYEPTFYGRLLASFPLSFDASILVVKFG 494

  Fly   870 KMMVL--GAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANH----QKALSGTKCSDHVAM--I 926
            :|.:|  |.:.|     .:|.:........|..|.......:|    .|.:||.: .:.|.|  .
plant   495 EMGMLRQGILLG-----VLMDTLPLPIHHPFGDDSLFLEYVDHYFGGSKTISGGR-REMVLMANF 553

  Fly   927 VASQMWRR---EKQRGEHM-------------------EARFCDWKGLQMST 956
            .|.|.|:|   :|.|.|::                   |..:||:..:..|:
plant   554 CAFQFWQRVFKDKHRLENLKQLLSKEKDKDLKLMFPEIEKEWCDFHNIAQSS 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684
		DEXHc_DHX9	326..559	CDD:350730	70/180 (39%)
		HrpA	378..>889	CDD:441249	159/540 (29%)
		OB_NTP_bind	1002..1079	CDD:400182
AT2G47680	NP_182290.1	HrpA	24..>482	CDD:441249	152/506 (30%)
		DEXHc_RHA-like	42..188	CDD:438707	60/153 (39%)
		YTH1	624..>779	CDD:227416