Protein Alignment mle and AT2G01130

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_178223.2
• Gene: AT2G01130 / 814642
• AraportID: AT2G01130
• Length: 1113
• Species: Arabidopsis thaliana
• Alignment Length: 1086
• Identity: 363/1086 - (33%)
• Similarity: 553/1086 - (50%)
• Gaps: 161/1086 - (14%)

  Fly   186 DYKYTPV-------------------GPEHARSFLAELS--------IYVPALNRTVTARESGSN 223
            ||.:.||                   .|:......|:|.        :...:|.:.|.:||. .:
plant    20 DYGFNPVPLSPVRYVSAYDDRVSEDRQPQEGTFHCADLDDWNKRFSMLLKDSLKQEVISREK-KD 83

  Fly   224 KKSASKSCALSLVRQLF---HLNVI-------EPFSGTLKKKKDEQLKPYPVKLSPNLINKIDEV 278
            ::...|..||:....|:   :..|:       ..:...|..||.::    .|.|..:|:.:::..
plant    84 RRDFDKLAALATTLGLYSHAYAKVVVFSKIPLPNYRFDLDDKKPQR----EVNLHTDLLQRVEAY 144

  Fly   279 IKGLDLPVVNPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKRQE--SSVIPWAPPQANWNTWHAC 341
            :...                    |..:.:|||....:...|..  ||...|...|
plant   145 LTEY--------------------LSKSSNRIDRVPANSVSRTSSISSTDEWFSEQ--------- 180

  Fly   342 NIDEGELATTSIDDLSMDYERS--LRDRR---QNDNEYRQFLEFREKLPIAAMRSEILTAINDNP 401
                    ...|....:.::||  ||||:   |...|.::.|:.|..||....|..:||||:.|.
plant   181 --------PLPISATKILWQRSLQLRDRQQYWQASVEGQRMLDSRTSLPAFKQRHSVLTAISQNQ 237

  Fly   402 VVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVG 466
            |::|.|.|||||||||.|:||:..|.:.:|.:::|..||||||||:||:||||.||.||||::||
plant   238 VIVISGETGCGKTTQIPQFILESEIEANRGAFSSIICTQPRRISAMSVSERVAYERGEQLGESVG 302

  Fly   467 YSVRFESVFPRPYGAILFCTVGVLLRKL--EAGLRGVSHIIVDEIHERDVNSDFLLVILRDMVDT 529
            |.||.|.|..|. ..:||||.|:|||:|  :..||||:|:||||||||.:|.||||:||:|::..
plant   303 YKVRLEGVKGRD-TRLLFCTTGILLRRLLVDRNLRGVTHVIVDEIHERGMNEDFLLIILKDLLSR 366

  Fly   530 YPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDF--VPSAESRRKRKE 592
            ..:|.:||||||:|...||.|||...|:.:||..:||:..|||||::||.:  .|       ..:
plant   367 RSELKLILMSATLDAELFSSYFGGAGVIYIPGFTYPVRSHFLEDILEMTRYRLTP-------YNQ 424

  Fly   593 VED--EEQLLSEDKD-----EAEINYNKVCED--------KYSQKTRNAMAMLSESDVSFELLEA 642
            ::|  :|:....:|.     :::|.:  |.||        ::|.:||.:::......:.|.|:|.
plant   425 IDDYGQERTWKMNKQIPKKRKSQITF--VVEDALRAADFKEFSPETRESLSCWYPDCIGFNLIEF 487

  Fly   643 LLMHIKSKNIPGAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVP 707
            ||.:|.....||.||:||.||:.|.:|.:.||...|||:.....:|.||..:...|||.:||...
plant   488 LLCNICENEGPGGILIFLTGWDDISSLKEKLQIHPIFGNPDLVMLLACHGSMETFEQRLIFEEPA 552

  Fly   708 EGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRV 772
            .||.||:|:||||||||||:|:.||||..||:...:.:.||.......|.||.:.:||:||||||
plant   553 SGVRKIVLATNIAETSITINDVAFVIDCGKAKETSYDALNNTPCLLPSWISKVSAQQRRGRAGRV 617

  Fly   773 RPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAE 837
            |||.|:.|..:..:.|..:...||:.|||||.:.|.||.|.||||..|||:||:.|.:.||.:|.
plant   618 RPGQCYHLYPKCVYDAFAEYQLPEILRTPLHSLCLQIKSLNLGSISEFLSRALQSPELLAVQKAI 682

  Fly   838 VLLREMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCAD-LMAIMASYSSTFSEVFSLD 901
            ..|:.:..||.|::||.|||.|::||:||:||||::|||:.||.| ::.:.|..|  ..:.|...
plant   683 AFLKIIGALDENEDLTTLGRYLSKLPMEPKLGKMLILGAILGCLDPILTVAAGLS--VRDPFLTP 745

  Fly   902 IGQRRLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKG-LQMSTMNVIWDAKQ 965
            ..::.||...|:......|||:|::.|.:.|::.::  |.....:| ||. |.:.::..|...::
plant   746 QDKKDLAEAAKSQFSRDHSDHLALVRAYEGWKKAEE--ESAVYDYC-WKNFLSIQSLRAIDSLRK 807

  Fly   966 QLLDLLQQAGF----PEECMISHEVDERIDGDDPVLDVSLALLCLGLYPNIC--VHKEKR-KVLT 1023
            :...||:..|.    |..|        ..:|:|  .:::.|::|.|:||.||  ||.|:. .:.|
plant   808 EFFSLLKDTGLIDGNPSIC--------NSEGND--ANLTRAVICYGMYPGICSVVHNERSFSLKT 862

  Fly  1024 TESKAALLHKTSVNCSNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPLQVILFGS--RKIDLAA 1086
            .|....||:..|.|.....:  |||:.||.|||:..:|..:..:..|...:||||.  .|.| ..
plant   863 MEDGQVLLYSNSENARETKI--PYPWLVFNEKIKVNSVFLRDSTACSDSTLILFGGSISKGD-TD 924

  Fly  1087 NNIVRVDNWLNFDIEPELAAKIGALKPALEDLITVACDNPS-DILRLEEPYAQLVKVVKDLCVKS 1150
            .::..:..:|.|.::|::|.....||..|::||.....||. |:    :.:.:|:..::.|..:.
plant   925 GHLKMLGGYLEFFMKPDVAEIYQTLKKELDELIQNKLLNPKVDM----QAHRELLSAIRLLVSED 985

  Fly  1151 AGD----FGLQ----RESGILPHQ----SRQFSDGGGPPKRGRFET 1184
            ..|    ||.|    .|...|..:    ||..|..||...:.:.:|
plant   986 GCDGRFVFGHQILRPLEISALSTKPSLFSRTESGPGGDNSKSQLQT 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684	15/84 (18%)
		DEXHc_DHX9	326..559	CDD:350730	111/239 (46%)
		HrpA	378..>889	CDD:441249	240/530 (45%)
		OB_NTP_bind	1002..1079	CDD:400182	29/79 (37%)
AT2G01130	NP_178223.2	HrpA	218..>817	CDD:441249	258/613 (42%)
		OB_NTP_bind	837..918	CDD:400182	30/82 (37%)
		dsrm	1025..1087	CDD:425434	1/7 (14%)