Sequence 1: | NP_476641.1 | Gene: | mle / 35523 | FlyBaseID: | FBgn0002774 | Length: | 1293 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | XP_011541883.1 | Gene: | YTHDC2 / 64848 | HGNCID: | 24721 | Length: | 1439 | Species: | Homo sapiens |
Alignment Length: | 1323 | Identity: | 381/1323 - (28%) |
---|---|---|---|
Similarity: | 551/1323 - (41%) | Gaps: | 399/1323 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 80 PADAGASGGGPRTGLEGAGMAGGSGQQKRVFDGQSGPQDLGEAYRPLNHDGGDGGNRYSVIDRIQ 144
Fly 145 EQRDMNEAEAFDVNAAIHGNWTIENAKERLNIYKQTNNIRDDYKYTPVGPEHARSFLAELSIYVP 209
Fly 210 ALNRTVTARESGSNKKSASKSCALSLVRQLFHLNVIEPFSGTLKKKKDEQLKPYPVKLSPNLINK 274
Fly 275 IDEVIKGL--DLPVVNPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKRQESSV-------IPWAP 330
Fly 331 PQANWNTWHACNIDEGELATTSIDDLSMDYERSLRDRRQNDNEYRQFLEFREKLPIAAMRSEILT 395
Fly 396 AINDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQ 460
Fly 461 LGDTVGYSVRFES-VFPRPYGAILFCTVGVLLRKLEAG---LRGVSHIIVDEIHERDVNSDFLLV 521
Fly 522 ILRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMT-------- 578
Fly 579 -------------------------DFVPSAESRRKRKEVEDEEQLLSEDKD-------EAEIN- 610
Fly 611 ----------------------------------YNKVCEDKYSQKTRNAMAM------------ 629
Fly 630 ---------------------------------------------LSE--------SDVSF---E 638
Fly 639 LLEA-------------LLMHIKSKNI-----PGAILVFLPGWNLIFALM-KFLQNTNIFGD-TS 683
Fly 684 QYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNN 748
Fly 749 LTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLR 813
Fly 814 LGS--IHHFLSKALEPPPVDAVIEAEVLLREMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGA 876
Fly 877 VFGCAD---LMAIMASYSSTFSEVFSLDIGQRRLAN-HQKALSGTKCSDHVAMIVASQMWRREKQ 937
Fly 938 RGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFPEECMISHEVDERIDGDDPVLDVSL- 1001
Fly 1002 --------ALLCLGLYPNICVHKEKRKVLTT--ESKAALLHKTSV------------NCSNLAV- 1043
Fly 1044 TFPYPFFVFGEKIRT-RAVSCKQLSMVSPLQVILF--------------GSRKIDLAANN----- 1088
Fly 1089 ----------IVRVDNWLNFDIEPELAAKIGALKPALEDLITVACDNPSDILRLEEPYAQL---- 1139
Fly 1140 VKVVKDLCVKSAGDFGLQRESGI 1162 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
mle | NP_476641.1 | DSRM | 4..68 | CDD:214634 | |
DSRM | 170..240 | CDD:214634 | 11/69 (16%) | ||
DEXDc | 393..569 | CDD:214692 | 95/179 (53%) | ||
DEXDc | 402..542 | CDD:238005 | 80/143 (56%) | ||
ATP-synt_B | <584..644 | CDD:304375 | 21/182 (12%) | ||
Helicase_C | 643..772 | CDD:278689 | 64/135 (47%) | ||
HA2 | 842..926 | CDD:214852 | 30/87 (34%) | ||
OB_NTP_bind | 974..1078 | CDD:285018 | 31/142 (22%) | ||
YTHDC2 | XP_011541883.1 | R3H_DEXH_helicase | 46..104 | CDD:100077 | 14/96 (15%) |
HrpA | 189..>1016 | CDD:224557 | 295/847 (35%) | ||
DEXHc_YTHDC2 | 193..368 | CDD:350745 | 94/178 (53%) | ||
ANK repeat | 505..537 | CDD:293786 | 1/31 (3%) | ||
ANK repeat | 539..564 | CDD:293786 | 0/24 (0%) | ||
OB_NTP_bind | 971..1066 | CDD:369483 | 23/95 (24%) | ||
YTH | 1288..1404 | CDD:367840 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG1643 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D222681at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.820 |