DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mle and T07D4.5

DIOPT Version :9

Sequence 1:	NP_476641.1	Gene:	mle / 35523	FlyBaseID:	FBgn0002774	Length:	1293	Species:	Drosophila melanogaster
Sequence 2:	NP_001122634.1	Gene:	T07D4.5 / 6418633	WormBaseID:	WBGene00045407	Length:	142	Species:	Caenorhabditis elegans

Alignment Length:	125	Identity:	28/125 - (22%)
Similarity:	44/125 - (35%)	Gaps:	40/125 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   691 HSQIPRDEQRKVFEPVPEGVTKIILSTNI---AETSITIDDIVFVIDICKARMKLFTSHNNLTSY 752
            :::.|.|.|:::.:...|   .|.|||.:   .||.:.:|                   |....:
Worm    13 NAKTPHDHQKELRDKTSE---IIYLSTKLNHAKETCVNLD-------------------NERQKF 55

  Fly   753 ATVWASKTNLEQRKGRAGRVRP-----GFCFTLCSRAR-FQALE-DNLTPEMFRTPLHEM 805
            ..|        .||.:...:.|     |.||...|:|. ...|| |..|.|..|..:.|:
Worm    56 REV--------SRKIKEKDIDPVWIYNGTCFLQTSQANSLNILEKDTKTVEEVRGQIQEV 107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM	4..68	CDD:214634
		DSRM	170..240	CDD:214634
		DEXDc	393..569	CDD:214692
		DEXDc	402..542	CDD:238005
		ATP-synt_B	<584..644	CDD:304375
		Helicase_C	643..772	CDD:278689	15/83 (18%)
		HA2	842..926	CDD:214852
		OB_NTP_bind	974..1078	CDD:285018
T07D4.5	NP_001122634.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900