Sequence 1: | NP_476641.1 | Gene: | mle / 35523 | FlyBaseID: | FBgn0002774 | Length: | 1293 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_064547.2 | Gene: | DHX33 / 56919 | HGNCID: | 16718 | Length: | 707 | Species: | Homo sapiens |
Alignment Length: | 641 | Identity: | 190/641 - (29%) |
---|---|---|---|
Similarity: | 301/641 - (46%) | Gaps: | 110/641 - (17%) |
- Green bases have known domain annotations that are detailed below.
Fly 367 RRQ-------NDNEYRQFLEF-REKLPIAAMRSEILTAIN--DNPVVIIRGNTGCGKTTQIAQYI 421
Fly 422 LDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCT 486
Fly 487 VGVLLRKL--EAGLRGVSHIIVDEIHERDVNSDFLLVIL------RDMVDTYPDLHVILMSATID 543
Fly 544 TTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAE 608
Fly 609 INYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGA--ILVFLPGWNLIFALMK 671
Fly 672 FLQNTNIFGDTSQY--------QILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDD 728
Fly 729 IVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQALEDNL 793
Fly 794 TPEMFRTPLHEMALTIKLLRLGSI--HHFLSKALEPPPVDAVIEAEVLLREMRCLDANDELTPLG 856
Fly 857 RLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSD 921
Fly 922 HVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFP 977 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
mle | NP_476641.1 | DSRM | 4..68 | CDD:214634 | |
DSRM | 170..240 | CDD:214634 | |||
DEXDc | 393..569 | CDD:214692 | 82/185 (44%) | ||
DEXDc | 402..542 | CDD:238005 | 66/147 (45%) | ||
ATP-synt_B | <584..644 | CDD:304375 | 2/59 (3%) | ||
Helicase_C | 643..772 | CDD:278689 | 48/138 (35%) | ||
HA2 | 842..926 | CDD:214852 | 19/83 (23%) | ||
OB_NTP_bind | 974..1078 | CDD:285018 | 1/4 (25%) | ||
DHX33 | NP_064547.2 | Required for nucleolar location. /evidence=ECO:0000269|PubMed:26100019 | 1..80 | 9/30 (30%) | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..64 | 3/14 (21%) | |||
HrpA | 67..695 | CDD:224557 | 186/623 (30%) | ||
DEXDc | 92..234 | CDD:238005 | 67/149 (45%) | ||
DEAH box | 194..197 | 2/2 (100%) | |||
Helicase_C | 291..408 | CDD:278689 | 45/122 (37%) | ||
HA2, required for interaction with EIF3G and RPL26. /evidence=ECO:0000269|PubMed:26100019 | 471..562 | 22/91 (24%) | |||
HA2 | 478..563 | CDD:214852 | 20/85 (24%) | ||
Critical for rDNA-binding. /evidence=ECO:0000250 | 547..558 | 1/11 (9%) | |||
OB_NTP_bind | 597..697 | CDD:285018 | 4/13 (31%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG1643 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |