DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mle and Y108F1.5

DIOPT Version :9

Sequence 1:	NP_476641.1	Gene:	mle / 35523	FlyBaseID:	FBgn0002774	Length:	1293	Species:	Drosophila melanogaster
Sequence 2:	NP_001361911.1	Gene:	Y108F1.5 / 353490	WormBaseID:	WBGene00022433	Length:	147	Species:	Caenorhabditis elegans

Alignment Length:	141	Identity:	38/141 - (26%)
Similarity:	66/141 - (46%)	Gaps:	17/141 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   839 LLREMRCLDANDELT-PLGRLLARLPIEPRLGKMMVLGAVFGC-ADLMAIMASYSSTFSEVFSLD 901
            ||..:..:|...:|| |||..:|..|:.|...|.::..|.||| .:::.|:|...  ..:||...
Worm     7 LLYALGAIDETSQLTSPLGLQMAEFPLPPMHSKCLLKSAEFGCFTEMVTIVAMMQ--IQDVFITP 69

  Fly   902 IGQRRLANHQKALSGTKCSDHVAMIVASQMW----RREKQRGEHMEARFCDWKGLQMSTMNVIWD 962
            ..||..|:..:.....:..:|:.|:.....:    |.:|...:|    |.:::|| |...||
Worm    70 YRQRHQADVIRKKFAVEEGNHITMLNVFTKFVENGRSKKWCSDH----FVNYRGL-MRADNV--- 126

  Fly   963 AKQQLLDLLQQ 973
             :.||:.||::
Worm   127 -RSQLVRLLKR 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM	4..68	CDD:214634
		DSRM	170..240	CDD:214634
		DEXDc	393..569	CDD:214692
		DEXDc	402..542	CDD:238005
		ATP-synt_B	<584..644	CDD:304375
		Helicase_C	643..772	CDD:278689
		HA2	842..926	CDD:214852	22/85 (26%)
		OB_NTP_bind	974..1078	CDD:285018	38/141 (27%)
Y108F1.5	NP_001361911.1	HrpA	<1..>144	CDD:224557	38/141 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900